半夏白术天麻汤联合颈椎定位旋转扳法对痰浊中阻型颈性眩晕患者的临床疗效  

Clinical effects of Banxia Baizhu Tianma Decoction combined with cervical spine positioning and rotation manipulation on patients with cervical vertigo due to Phlegem Turbidity Obstructing the Middle-Jiao

作　　者：刘效忠 郑吉利 陈逸霖 吴晓飞 林彬[1] LIU Xiao-zhong;ZHENG Ji-li;CHEN Yi-lin;WU Xiao-fei;LIN Bin(Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Guangzhou Tianhe District Hospital of Traditional Chinese Medicine,Guangzhou 510630,China)

机构地区：[1]广州中医药大学,广东广州510006 [2]广州市天河区中医医院,广东广州510630

出　　处：《中成药》2025年第1期86-90,共5页Chinese Traditional Patent Medicine

基　　金：广东省中医药局中医药科研项目(20231139);广州市哲学社会科学发展“十四五”规划2022年度共建课题(2022GZGJ184);2022-2023年科技创新和体育文化发展科研重点项目(GDSS2022M004)。

摘　　要：目的探讨半夏白术天麻汤联合颈椎定位旋转扳法对痰浊中阻型颈性眩晕患者的临床疗效。方法200例患者随机分为对照组和观察组,每组100例,2组均采用常规治疗,同时对照组给予颈椎定位旋转扳法,观察组在对照组基础上加用半夏白术天麻汤,疗程1个月。检测临床疗效、ESCV评分、DHI评分、椎基底动脉血流速度(右椎动脉、基底动脉、左椎动脉)、血液流变学指标(纤维蛋白原、血浆比黏度、红细胞压积)、PGI 2、CGRP、EDHF、NPY、安全性指标变化。结果观察组总有效率高于对照组(P<0.05)。治疗后,2组DHI评分、血液流变学指标、NPY降低(P<0.05),ESCV评分、椎基底动脉血流速度、PGI 2、CGRP、EDHF升高(P<0.05),以观察组更明显(P<0.05)。2组安全性指标无明显异常。结论半夏白术天麻汤联合颈椎定位旋转扳法可安全有效地调节痰浊中阻型颈性眩晕患者舒张血管因子、收缩血管因子水平,改善椎基底动脉血流速度、血液流变学指标及血液循环,缓解眩晕,提升生活质量及临床疗效。AIM To explore the clinical effects of Banxia Baizhu Tianma Decoction combined with cervical spine positioning and rotation manipulation on patients with cervical vertigo due to Phlegem Turbidity Obstructing the Middle-Jiao.METHODS Two hundred patients were randomly assigned into control group(100 cases)for 1-month intervention of both cervical spine positioning and rotation manipulation and conventional treatment,and observation group(100 cases)for 1-month intervention of Banxia Baizhu Tianma Decoction,cervical spine positioning and rotation manipulation and conventional treatment.The changes in clinical effects,ESCV score,DHI score,vertebrar basilar artery blood flow velocities(right vertebral artery,basilar artery,left vertebral artery),hemorheological indices(fibrinogen,plasma specific viscosity,hematocrit),PGI 2,CGRP,EDHF,NPY and safety indices were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P<0.05).After the treatment,the two groups displayed decreased DHI score,hemorheological indices,NPY(P<0.05),and increased ESCV score,vertebrar basilar artery blood flow velocities,PGI 2,CGRP,EDHF(P<0.05),especially for the observation group(P<0.05).No obvious abnormalities were observable in safety indices of the two groups.CONCLUSION For the patients with cervical vertigo due to Phlegem Turbidity Obstructing the Middle-Jiao,Banxia Baizhu Tianma Decoction combined with cervical spine positioning and rotation manipulation can safely and effectively regulate vasodilator factor,vasoconstrictor factor levels,improve vertebrar basilar artery blood flow velocities,hemorheological indices,blood circulation,alleviate dizziness,and enhance life quality and clinical effects.

关 键 词：半夏白术天麻汤 颈椎定位旋转扳法 颈性眩晕 痰浊中阻 椎基底动脉血流 血液流变学 

分 类 号：R287[医药卫生—中药学]