直接抽吸技术作为首选取栓策略在急性后循环大血管闭塞的可行性与安全性研究  

Direct aspiration therapy used as a preferred thrombectomy strategy for acute posterior circulation-large vessel occlusion:analysis of its clinical feasibility and safety

作　　者：韦丽丽 班邓荣 刘艺 李登星 杨琴 李绍发[2] 黄志志[2] 廖宝 WEI Lili;BAN Dengrong;LIU Yi;LI Dengxing;YANG Qin;LI Shaofa;HUANG Zhizhi;LIAO Bao(Department of Neurology,Youjiang Medical University For Nationalities,Youjiang,Baise Municipal People′s Hospital,Baise,Guangxi Zhuang Autonomous Region 533000,China)

机构地区：[1]右江民族医学院,广西百色533000 [2]百色市人民医院

出　　处：《介入放射学杂志》2024年第12期1320-1325,共6页Journal of Interventional Radiology

基　　金：广西壮族自治区卫生健康委员会计划项目(Z20200209)。

摘　　要：目的探讨直接抽吸技术作为急性后循环大血管闭塞(posterior circulation-large vessel occlusion,PC-LVO)患者首选策略的可行性和安全性。方法研究纳入2020年1月至2022年12月百色市人民医院神经内科收治的采用直接抽吸技术作为首选取栓策略的急性PC-LVO患者,采集所有纳入患者的基线资料,记录手术流程和相关参数,评估手术的有效性、安全性和预后。结果共纳入36例患者,平均年龄61.31岁,男性占75.0%。发病至穿刺的中位时间419.5 min,穿刺至血管再通的中位时间60 min。血管再通率达91.7%,症状性颅内出血率11.1%,操作并发症发生率8.3%。90 d良好预后(mRS评分≤3分)的患者占41.7%,病死率25%。结论直接抽吸技术作为PC-LVO机械取栓治疗的首选策略,具有较高的血管再通率和可接受的安全性。Objective To investigate the clinical feasibility and safety of direct aspiration thrombectomy used as a preferred strategy for patients with acute posterior circulation-large vessel occlusion(PC-LVO).Methods The patients with acute PC-LVO,who received direct aspiration therapy as the preferred thrombectomy strategy at the Department of Neurology,Baise Municipal People′s Hospital of China from January 2020 to December 2022,were enrolled in this study.The baseline data were collected from all the included patients,and the surgical procedure and related parameters were recorded,the clinical effectiveness,safety and prognosis were evaluated.Results A total of 36 patients were included in this study with an average age of 61.31 years,and 75.0%of them were males.The median time from the onset of disease to the perform of puncturing was 419.5 minutes,and the median time from puncturing to vessel recanalization was 60 minutes.The vascular recanalization rate was up to 91.7%,the incidence of symptomatic intracranial hemorrhage was 11.1%,and the incidence of operation-related complications was 8.3%.The postoperative 90-day good prognosis(mRS score≤3 points)was obtained in 41.7%of patients,and the mortality rate was 25%.Conclusion For patients with acute PC-LVO,direct aspiration therapy used as the preferred strategy of mechanical thrombectomy has a high vascular recanalization rate and an acceptable safety.

关 键 词：后循环 大血管闭塞 直接抽吸 取栓 补救措施 

分 类 号：R654.3[医药卫生—外科学]