苍附导痰汤加减治疗对肥胖型多囊卵巢综合征患者卵巢功能与体质指数的影响  

Effects of Modified Cangfu Daotan Decoction on Ovarian Function and Body Mass Index in Obese Polycystic Ovary Syndrome Patients

作　　者：房彩平[1] 朱虹 FANG Caiping;ZHU Hong(Department of Obstetrics and Gynecology,Taizhou Hospital of Traditional Chinese Medicine,Taizhou 225300,China)

机构地区：[1]泰州市中医院妇产科,江苏泰州225300

出　　处：《反射疗法与康复医学》2024年第20期13-16,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨苍附导痰汤加减治疗肥胖型多囊卵巢综合征(PCOS)的临床效果。方法选取2022年5月—2024年3月泰州市中医院收治的88例肥胖型PCOS患者为研究对象,按随机数字表法将其分为对照组和观察组,各44例。对照组采用口服达英-35治疗,观察组在对照组的基础上采用苍附导痰汤加减治疗,两组均持续治疗3个月。对比两组的临床疗效、卵巢功能、体质指数(BMI)、卵巢体积、卵泡数目及不良反应发生情况。结果观察组治疗总有效率为95.45%,高于对照组的81.82%,差异有统计学意义(P<0.05)。治疗后,观察组促卵泡激素为(7.76±1.18)miu/mL,雌二醇为(105.43±9.72)pmol/L,均高于对照组的(6.65±1.07)miu/mL、(89.72±9.15)pmol/L,黄体生成素为(9.02±1.13)miu/mL,睾酮为(1.69±0.22)nmol/L,均低于对照组的(11.38±1.22)miu/mL、(2.51±0.43)nmol/L,组间差异有统计学意义(P<0.05);观察组BMI、卵巢体积分别为(25.63±1.41)kg/m^(2)、(5.52±1.02)cm^(3),均小于对照组的(28.62±1.45)kg/m^(2)、(7.61±1.18)cm^(3),卵泡数目为(8.32±1.28)个,少于对照组的(11.07±1.46)个,组间差异有统计意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论苍附导痰汤加减治疗肥胖型PCOS患者,可提升治疗效果,改善卵巢功能,降低BMI,且安全可靠。Objective To explore the clinical effect of modified Cangfu Daotan decoction on obese polycystic ovary syndrome(PCOS).Methods A total of 88 obese PCOS patients admitted to Taizhou Hospital of Traditional Chinese Medicine from May 2022 to March 2024 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 44 cases in each group.The control group was treated with oral Danyin-35,and the observation group was treated with modified Cangfu Daotan decoction on the basis of the control group,both groups were treated for 3 months.The clinical efficacy,ovarian function,body mass index(BMI),ovarian volume,number of follicles and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 95.45%,which was higher than 81.82%of the control group,and the difference was statistically significant(P<0.05).After treatment,follicle-stimulating hormone was(7.76±1.18)miu/mL and estradiol was(105.43±9.72)pmol/L in the observation group,which were higher than(6.65±1.07)miu/mL and(89.72±9.15)pmol/L in the control group,luteinizing hormone was(9.02±1.13)miu/mL and testosterone was(1.69±0.22)nmol/L,which were lower than(11.38±1.22)miu/mL and(2.51±0.43)nmol/L of control group,and the differences between the groups were statistically significant(P<0.05);the BMI and ovarian volume of the observation group were(25.63±1.41)kg/m^(2)and(5.52±1.02)cm^(3),which were lower than(28.62±1.45)kg/m^(2)and(7.61±1.18)cm^(3)of the control group,and the number of follicles was(8.32±1.28),which were less than(11.07±1.46)in the control group,and the differences between the groups were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion In the treatment of obese PCOS patients,modified Cangfu Daotan decoction can improve the therapeutic effect,improve ovarian function,reduce BMI,and is safe

关 键 词：多囊卵巢综合征 肥胖 苍附导痰汤加减 卵巢功能 

分 类 号：R711.75[医药卫生—妇产科学]