应重视反复妊娠丢失中的慢性子宫内膜炎因素  

Call attention to the role of chronic endometritis in recurrent pregnancy loss

作　　者：杨一华 黄伟育 Yang Yihua;Huang Weiyu(Reproductive Medicine Center,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第一附属医院生殖医学中心,南宁530021

出　　处：《中华医学杂志》2024年第39期3642-3646,共5页National Medical Journal of China

摘　　要：慢性子宫内膜炎(CE)是子宫内膜的持续性炎症,与女性不孕症和不良妊娠结局密切相关。反复妊娠丢失(RPL)是指同一对夫妇出现2次及以上孕20周前的妊娠丢失,其病因复杂。CE在RPL患者中检出率高达30%,提示CE造成的子宫内膜免疫微环境的失衡可能是导致RPL的重要原因。因此,临床工作中我们应重视对RPL患者进行CE筛查,并给予相应的治疗。然而,由于CE的诊断标准尚未统一,业内对CE及其与RPL的关系仍存在争议。CE的治疗以抗生素为主,采取较高的CE诊断界值能保证RPL患者得到有效治疗的同时避免抗生素的滥用,CE的有效治疗能改善RPL患者妊娠结局。Chronic endometritis(CE)refers to the persistent inflammation of endometrium and is closely associated with infertility.Recurrent pregnancy loss(RPL),which has complex etiological factors,is two or more pregnancy loss of a couple before 20 weeks.However,CE is found in approximately 30%RPL patients,indicating that the endometrial immune microenvironment disorder caused by CE may play important role in RPL.Therefore,we should pay high attention and give CE screening to the RPL patients.Due to the inconsistent diagnostic criteria of CE,the relationship between RPL and CE remains controversial.Antibiotic is the primary treatment of CE.Using the higher CE diagnosis value can ensure effective treatment to RPL patient,and avoid the abuse of antibiotic.The effective treatment of CE can improve the pregnant outcomes of RPL patient.

关 键 词：子宫内膜炎 慢性子宫内膜炎 妊娠丢失 人工智能 诊治 

分 类 号：R71[医药卫生—妇产科学]