盐酸氨基葡萄糖治疗膝关节半月板损伤患者的临床效果分析  

Analysis of the clinical effect of glucosamine hydrochloride treatment on patients with meniscus knee injury

作　　者：徐敏 XU Min(Rehabilitation Medicine Department,Linyi Central Hospital,Linyi 276400,China)

机构地区：[1]临沂市中心医院康复医学科,276400

出　　处：《中国实用医药》2025年第1期21-25,共5页China Practical Medicine

摘　　要：目的分析膝关节半月板损伤患者应用盐酸氨基葡萄糖治疗的疗效。方法90例膝关节半月板损伤患者,根据随机数字表法分为对照组和观察组,每组45例。对照组仅用非甾体类消炎药治疗,观察组应用非甾体类消炎药联合盐酸氨基葡萄糖治疗。比较两组疼痛情况、膝关节功能、不良反应发生率、屈曲角度、步行稳定性。结果治疗后,两组数字疼痛强度量表(NRS)评分均低于本组治疗前,Lysholm膝关节评分高于本组治疗前,且观察组NRS评分(3.21±1.05)分低于对照组的(4.67±0.78)分,Lysholm膝关节评分(82.17±4.51)分高于对照组的(64.34±5.19)分(P<0.05)。治疗后,两组膝关节协会评分(KSS评分)高于本组治疗前,美国西部Ontario和McMaster大学骨关节指数量表(WOMAC)评分低于本组治疗前,且观察组KSS评分(91.33±1.65)分高于对照组的(86.27±1.79)分,WOMAC评分(54.33±1.79)分低于对照组的(66.05±1.89)分(P<0.05)。观察组不良反应发生率4.44%低于对照组的20.00%(P<0.05)。治疗后,两组屈曲角度、步行稳定性评分高于本组治疗前,且观察组屈曲角度(131.21±2.76)°、步行稳定性评分(4.78±0.38)分高于对照组的(125.65±1.56)°、(4.02±0.29)分(P<0.05)。结论膝关节半月板损伤患者应用盐酸氨基葡萄糖治疗的效果较好,可以降低患者疼痛程度,改善膝关节功能,减少不良反应的发生。Objective To analyze the curative effect of glucosamine hydrochloride treatment on patients with meniscus knee injury.Methods 90 patients with meniscus knee injury were randomly assigned to control group and observation group according to random numerical table,with 45 cases in each group.Patients in the control group were given non-steroidal anti-inflammatory drugs alone,while those in the observation group were given non-steroidal anti-inflammatory drugs and glucosamine hydrochloride.The pain,knee function,incidence of adverse reactions,flexion angle and walking stability were compared between the two groups.Results After treatment,the score of numerical rating scale(NRS)in both groups was lower than that before treatment,and the Lysholm knee score was higher than that before treatment;NRS score of(3.21±1.05)points in the observation group was lower than(4.67±0.78)points in the control group,and Lysholm knee score of(82.17±4.51)points was higher than(64.34±5.19)points in the control group(P<0.05).After treatment,the score of Knee Socirty Score(KSS)in both groups was higher than that before treatment,and the score of Western Ontario and McMaster University Osteoarthritis Index(WOMAC)was lower than that before treatment;KSS score of(91.33±1.65)points in the observation group was higher than(86.27±1.79)points in the control group,and WOMAC score of(54.33±1.79)points in the observation group was lower than(66.05±1.89)points in the control group(P<0.05).The incidence of adverse reactions of 4.44%in the observation group was lower than 20.00%in the control group(P<0.05).After treatment,the flexion angle and walking stability score in both groups were higher than those before treatment;the observation group had a flexion angle of(131.21±2.76)°and a walking stability score of(4.78±0.38)points,which were higher than(125.65±1.56)°and(4.02±0.29)points in the control group(P<0.05).Conclusion Glucosamine hydrochloride has a good therapeutic effect in treating meniscus knee injury.It can decrease the pain,enhan

关 键 词：膝关节半月板损伤 盐酸氨基葡萄糖 效果 膝关节功能 

分 类 号：R68[医药卫生—骨科学]