血常规联合CRP和AA检测对急性上呼吸道感染的诊断意义  

Diagnostic significance of blood routine combined with CRP and AA in acute upper respiratory tract infection

作　　者：何青青 白伟娜 李萍 HE Qingqing;BAI Weina;LI Ping(Department of Infectious Diseases,Beijing Jingmei Group General Hospital,Beijing 102300,China)

机构地区：[1]北京京煤集团总医院感染科,北京102300

出　　处：《医药前沿》2025年第4期33-35,39,共4页Journal of Frontiers of Medicine

基　　金：北京京煤集团总医院院级科研自主项目(ZZ2023-40)。

摘　　要：目的探讨血常规联合C反应蛋白(CRP)和淀粉样蛋白A(AA)检测对急性上呼吸道感染的诊断意义。方法选取2023年4月—2024年4月北京京煤集团总医院发热门诊收治的906例急性上呼吸道感染患者,根据病原学诊断结果分为细菌感染组(n=327)、病毒感染组(n=310)和支原体感染组(n=269)。比较3组患者血白细胞计数、淋巴细胞计数、中性粒细胞计数和CRP、AA水平,以及以上指标的分布情况。结果病毒感染组和支原体感染组血白细胞计数、淋巴细胞计数和中性粒细胞计数均低于细菌感染组,支原体感染组血白细胞计数和中性粒细胞计数均高于病毒感染组;病毒感染组CPR和AA水平低于细菌感染组和支原体感染组,差异有统计学意义(P<0.05)。细菌感染组和病毒感染组的血白细胞计数、淋巴细胞计数、中性粒细胞计数和CRP、AA水平分布比较,差异有统计学意义(P<0.05);细菌感染组和支原体感染组血白细胞计数、淋巴细胞计数、中性粒细胞计数和CRP水平分布比较,差异有统计学意义(P<0.05);病毒感染组和支原体感染组血白细胞计数、淋巴细胞计数、中性粒细胞计数和CRP、AA水平分布比较,差异有统计学意义(P<0.05)。结论血常规联合CRP和AA检测可以提高急性上呼吸道感染患者的病原体早期识别率,为其诊断和鉴别诊断提供参考依据,有利于后续治疗的实施。Objective To investigate the diagnostic significance of blood routine combined with C reactive protein(CRP)and amyloid A(AA)in acute upper respiratory tract infection.Methods A total of 906 patients with acute upper respiratory tract infection admitted to the fever clinic of Beijing Jingmei Group General Hospital from April 2023 to April 2024 were selected.According to the results of etiological diagnosis,they were divided into bacterial infection group(n=327),viral infection group(n=310)and mycoplasma infection group(n=269).The serum white blood cell count,lymphocyte count,neutrophil count,CRP and AA levels,and the distribution of the above indicators were compared among the three groups.Results The serum white blood cell count,lymphocyte count and neutrophil count in the viral infection group and the mycoplasma infection group were lower than those in the bacterial infection group,and the serum white blood cell count and neutrophil count in the mycoplasma infection group were higher than those in the viral infection group.The levels of CPR and AA in the viral infection group were lower than those in the bacterial infection group and the mycoplasma infection group,the differences were statistically significant(P<0.05).There were significant differences in serum white blood cell count,lymphocyte count,neutrophil count,CRP and AA levels between the bacterial infection group and the viral infection group(P<0.05).There were significant differences in serum white blood cell count,lymphocyte count,neutrophil count and CRP level distribution between bacterial infection group and mycoplasma infection group(P<0.05).There were statistically significant differences in serum white blood cell count,lymphocyte count,neutrophil count and distribution of CRP and AA levels between virus infection group and mycoplasma infection group(P<0.05).Conclusions Blood routine combined with CRP and AA detection can improve the early identification rate of pathogens in patients with acute upper respiratory tract infection,provide reference

关 键 词：上呼吸道感染 急性 诊断 白细胞计数 淋巴细胞计数 中性粒细胞计数 C反应蛋白 淀粉样蛋白A 

分 类 号：R63[医药卫生—外科学]