血清白蛋白与血红蛋白水平在评估透析患者营养状态与贫血管理中的意义  

Significance of serum albumin and hemoglobin levels in the assessment of nutritional status and anemia management in dialysis patients

作　　者：崔冰[1] 陈铸[2] 韩洋 Cui Bing;Chen Zhu;Han Yang(Blood Purification Center,The First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450000,China;Department of Urology,The First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第一附属医院血液净化中心,河南郑州450000 [2]河南中医药大学第一附属医院泌尿外科,河南郑州450000

出　　处：《四川生理科学杂志》2025年第1期54-56,共3页

摘　　要：目的:探讨血清白蛋白(Albumin,Alb)与血红蛋白(Hemoglobin,HB)水平在评估透析患者营养状态及贫血管理中的意义。方法:回顾性收集2022年1月-2024年6月在本院进行血液透析的112例患者的临床资料纳入观察组。另选取同期在本院进行体检的健康人群110例为对照组。检测两组的Alb、HB水平。采用营养评估工具[肱三头肌皮褶厚度(Triceps skin-fold thickness,TSF)、上臂围(Arm Circumference,AC)、上臂肌围(Arm Muscle Circumference,AMC)]评估两组的营养状态。采用血常规检查[红细胞数量、红细胞积压、转铁蛋白(Serum Transferrin,TF)]评估贫血指标。采用Pearson相关性分析透析患者血清Alb、HB与上述指标的相关性。结果:观察组Alb、HB、TF、红细胞数量、红细胞积压水平低于对照组(P<0.05);观察组TSF比对照组厚,AC、AMC比对照组大(P<0.05);根据Pearson相关性分析可得:Alb、HB均与TSF、AC、AMC、TF、红细胞数量、红细胞积压呈正相关(P<0.05)。结论:血清Alb和HB是评估血液透析患者营养状态和贫血状况的重要生物标志物,其水平变化可为临床治疗提供有价值的参考依据。Objective:To investigate the significance of serum Albumin(Alb)and Hemoglobin(HB)levels in the assessment of nutritional status and management of anemia in dialysis patients.Methods:The clinical data of 112 patients undergoing hemodialysis in our hospital from January 2022 to June 2024 were retrospectively collected and included into the observation group.Another 110 healthy people who underwent physical examination in our hospital during the same period were selected as the control group.The Alb and HB levels of the two groups were detected.Nutritional assessment tools[Triceps skin-fold thickness,triceps skin-fold thickness,TSF,Arm Circumference(AC)and Arm Muscle Circumference(AMC)]were used to evaluate the nutritional status of the two groups.Serum Transferrin(TF)and erythrocyte count were evaluated using routine blood tests.Pearson correlation was used to analyze the correlation between serum Alb,HB and the above indexes in dialysis patients.Results A:lb,HB,TF,red blood cell number and red blood cell backlog in observation group were lower than those in control group(P<0.05).The TSF of the observation group was thicker than that of the control group,and the AC and AMC were higher than that of the control group(P<0.05).According to Pearson correlation analysis,Alb and HB were positively correlated with TSF,AC,AMC,TF,red blood cell number and red blood cell backlog(P<0.05).Conclusion:Serum Alb and HB are important biomarkers to evaluate the nutritional status and anemia status of hemodialysis patients,and the changes of their levels can provide valuable reference for clinical treatment.

关 键 词：白蛋白 血红蛋白 透析患者 营养状态 贫血管理 

分 类 号：R459.5[医药卫生—治疗学]