棘突球囊预扩张对重度CAC冠心病患者疗效、MACE的影响  

Effect of spinous process balloon predilation on the efficacy and MACE in patients with severe CAC coronary heart disease

作　　者：张雪生[1] 李洋 徐亚谦 张文广[1] ZHANG Xue-sheng;LI Yang;XU Ya-qian;ZHANG Wen-guang(Department of Cardiology,Beijing Pinggu District Hospital,Beijing,101200,China)

机构地区：[1]北京市平谷区医院心内科,北京101200 [2]北京市平谷区医院高压氧科,北京101200

出　　处：《心血管康复医学杂志》2025年第1期42-46,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:比较重度冠状动脉钙化(CAC)冠心病患者应用普通球囊预扩张与棘突球囊预扩张的效果以及对短期主要不良心血管事件(MACE)的影响。方法:回顾性选择2017年1月-2022年1月期间于北京市平谷区医院行经皮冠状动脉介入治疗(PCI)治疗的重度CAC冠心病患者110例,并根据治疗方案分为棘突球囊组(n=55)、普通球囊组(n=55),分别应用相应的球囊预扩张PCI。对比两组的应用效果、围术期并发症及6个月的MACE发生情况。结果:棘突球囊组患者的手术即刻成功率显著高于普通球囊组(92.73%比78.18%,P=0.031)。与普通球囊组,棘突球囊组患者的球囊预扩张次数[(2.79±0.14)次比(7.29±2.24)次]、手术时间[(1.24±0.29)h比(1.59±0.34)h]和围术期并发症发生率(3.64%比14.55%)显著减少,术后的管腔直径[(3.79±0.26)mm比(3.29±0.24)mm]显著更大(P<0.05或<0.01)。两组患者的6个月MACE发生率无统计学差异(P=0.428)。结论:重度冠状动脉钙化冠心病患者应用棘突球囊预扩张可显著减少球囊预扩张次数、手术时间,提高手术成功率并降低短期MACE发生风险。Objective:This study aims to compare the efficacy on patients with severe coronary artery calcification(CAC)coronary heart disease(CHD)between common balloon predilation and spinous process balloon predilation and their effect on short-term incidence of major adverse cardiovascular events(MACE).Methods:This retrospective study enrolled 110 severe CAC patients with CHD who underwent percutaneous coronary intervention(PCI)in Beijing Pinggu District Hospital between January 2017 and January 2022.According to therapeutic program,they were divided into spinous process balloon group(n=55)and common balloon group(n=55),each group received corresponding balloon predilation before PCI.Application effect,perioperative complications and incidence of MACE within 6 months were compared between two groups.Results:Immediate surgical success rate in spinous process balloon group was significantly higher than that of common ballon group(92.73%vs.78.18%,P=0.031).Compared with patients in common balloon group,those in spinous process balloon group had significant lower times of balloon predilation[(2.79±0.14)times vs.(7.29±2.24)times],operation time[(1.24±0.29)h vs.(1.59±0.34)h]and incidence of perioperative complications(3.64%vs.14.55%),and significant larger lumen diameter after PCI[(3.79±0.26)mm vs.(3.29±0.24)mm](P<0.05 or<0.01).There was no significant difference in incidence of MACE within 6 months between two groups(P=0.428).Conclusion:The application of spinous process balloon predilation could significantly reduce times of balloon predilation,operation time,improve surgical success rate and reduce risk of short-term MACE in severe CAC patients with CHD.

关 键 词：冠心病 血管钙化 球囊扩张术 

分 类 号：R541.4[医药卫生—心血管疾病]