不同剂量酒石酸布托啡诺复合丙泊酚在老年无痛胃肠镜检查患者中的应用效果  

Effect of Different Doses of Butorphanol Tartrate Combined with Propofol in Elderly Patients Undergoing Painless Gastrointestinal Endoscopy

作　　者：范丽娜 张成功[1] 许兵 Fan Lina;Zhang Chenggong;Xu Bing(Kunming Hospital of Traditional Chinese Medicine,Kunming 650011,Yunnan Province,China)

机构地区：[1]昆明市中医医院,云南昆明650011

出　　处：《中外医药研究》2025年第2期67-69,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析不同剂量酒石酸布托啡诺复合丙泊酚在老年无痛胃肠镜检查患者中的应用效果。方法:选取昆明市中医医院2022年11月—2023年12月收治的60例老年无痛胃肠镜检查患者为研究对象,采用随机数字表法分为对照组和观察组,各30例。对照组予以1mg酒石酸布托啡诺复合丙泊酚,观察组予以0.5mg酒石酸布托啡诺复合丙泊酚。比较两组血流动力学指标、麻醉与镇静效果、不良反应发生率。结果:麻醉前(t_(0)),两组平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO_(2))水平对比,无统计学差异(P>0.05);诱导完成即刻(t_(1)),两组MAP、HR水平低于t_(0),观察组MAP、HR水平高于对照组(P<0.05);t_(1),两组SpO_(2)水平对比,无统计学差异(P>0.05);术毕(t_(2)),观察组MAP水平低于t_(0),对照组MAP、HR水平低于t_(0)(P<0.05);t_(2),两组MAP、HR水平对比,无统计学差异(P>0.05);t_(2),观察组SpO_(2)水平高于对照组(P<0.05)。两组检查用时、丙泊酚用量及停药5、30minRamsay评分比较,无统计学差异(P>0.05);观察组苏醒用时短于对照组(P<0.05);观察组停药10minRamsay评分高于对照组(P=0.023);观察组不良反应发生率低于对照组(P=0.038)。结论:无痛胃肠镜实施期间,为患者提供小剂量酒石酸布托啡诺复合丙泊酚麻醉,能够有效提高麻醉效果,降低对患者血流动力学的影响,减少不良反应。Objective:To analyze the effect of different doses of butorphanol tartrate combined with propofol in elderly patients undergoing painless gastrointestinal endoscopy.Methods:A total of 60 elderly patients undergoing painless gastrointestinal endoscopy admitted to Kunming Hospital of Traditional Chinese Medicine from November 2022 to December 2023 were selected as the research subjects.The patients were divided into a control group and an observation group by random number table method,with 30 cases in each group.The control group was given 1 mg butorphanol tartrate combined with propofol,and the observation group was given 0.5 mg butorphanol tartrate combined with propofol.The hemodynamic index,anesthetic and sedative effects,and the incidence of adverse reactions were compared between the two groups.Results:Before anesthesia(t_(0)),there was no statistical difference in mean arterial pressure(MAP),heart rate(HR),and blood oxygen saturation(SpO_(2))between the two groups(P>0.05).Immediately after induction(t_(1)),the MAP and HR levels of the two groups were lower than those of t_(0),and the MAP and HR levels of the observation group were higher than those of the control group(P<0.05).At t_(1),there was no statistical difference in SpO_(2) levels between the two groups(P>0.05).After surgery(t_(2)),the MAP level of the observation group was lower than that of t_(0),and the MAP and HR levels of the control group were lower than those of t_(0)(P<0.05).At t_(2),there was no statistical difference in MAP and HR levels between the two groups(P>0.05).At t_(2),the SpO_(2) level of the observation group was higher than that of the control group(P<0.05).There was no statistical difference in the examination time,propofol dosage,and Ramsay score at 5 and 30 min after drug withdrawal between the two groups(P>0.05).The awakening time of the observation group was shorter than that of the control group(P<0.05).The Ramsay score of the observation group after 10 min of drug withdrawal was higher than that of the control group(P=0.0

关 键 词：酒石酸布托啡诺 丙泊酚 老年 无痛胃肠镜 血流动力学 

分 类 号：R614[医药卫生—麻醉学]