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作 者:沈燕慧 洪丽美[1,2] 陈智颖 黄熙理[1,2] SHEN Yan-hui;HONG Li-mei;CHEN Zhi-ying;HUANG Xi-li(Zhangzhou Traditional Chinese Medicine Hospital Affiliated to Fujian University of Fraditional Chinese Medecine,Zhangzhou,363000,China;Department of Gynecology,Zhangzhou Traditional Chinese Medicine Hospital,Zhangzhou,363000,China)
机构地区:[1]福建中医药大学附属漳州中医院,漳州363000 [2]福建省漳州市中医院妇科,漳州363000
出 处:《神经药理学报》2024年第5期31-36,共6页Acta Neuropharmacologica
基 金:福建省卫健委医学创新课题(No.2020CXA056);黄熙理全国名老中医药专家传承工作室项目(No.国中医药人教函[2022]75号)。
摘 要:目的:挖掘黄熙理教授治疗慢性盆腔炎(chronic pelvic inflammatory disease,CPID)的用药规律。方法:收集2021年1月至2022年12月福建省漳州市中医院妇科黄熙理门诊治疗CPID的处方,运用中医传承辅助平台(V2.5)软件进行分析并总结用药规律。结果:共收集处方974首,涉及中药91味,四气以寒性为主,温性次之;五味以苦味最多,辛味次之。归经以肝经频次最高,其次为心经、脾经。关联规则分析共得到38对常用药物组合,基于熵聚类法得6个潜在新处方。结论:黄熙理教授以清热解毒利湿、养血活血化瘀、疏肝理气止痛为慢性盆腔炎主要治法,体现了黄教授以病为本,从脏论治,祛邪兼顾扶正的治疗理念。Objective:To explore the medication patterns of Professor Huang Xili in the treatment of chronic pelvic inflammatory disease(CPID).Methods:From January 2021 to December 2022,the prescriptions of Professor Huang Xili’s outpatient treatment of chronic pelvic inflammatory disease(CPID)were collected,and the TCM inheritance assistance platform(V2.5)software was used to analyze and summarize the medication rules.Results:A total of 974 prescriptions were collected,involving 91 kinds of traditional Chinese medicine.The four kinds of qi were mainly cold,followed by warm.Bitter taste was the most,spicy taste was the second.The frequency of hepatic channel was the highest,followed by spicy heart channel and spleen channel.A total of 38 pairs of common drug combinations were obtained by association rule analysis,and 6 potential new prescriptions were obtained based on entropy clustering method.Conclusion:Professor Huang Xili’s main treatment methods for chronic pelvic inflammatory disease include clearing heat,detoxifying,removing dampness,nourishing blood,promoting blood circulation,removing blood stasis,soothing the liver,regulating qi,and relieving pain.This reflects Professor Huang’s treatment philosophy of putting the disease first,treating from the perspective of the internal organs,and balancing the elimination of evil and the strengthening of the body.
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