新型除草剂rimisoxafen的合成与除草活性  

Synthesis and herbicidal activity of novel herbicide rimisoxafen

作　　者：英君伍 王继虓 梁爽 王刚 崔东亮 马宏娟 白晓晨 杨辉斌 YING Junwu;WANG Jixiao;LIANG Shuang;WANG Gang;CUI Dongliang;MA Hongjuan;BAI Xiaochen;YANG Huibin(National Engineering Research Center of Pesticide,State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Sinochem Agrochemicals R&D Co.,Ltd.,Shenyang 110021,China)

机构地区：[1]沈阳中化农药化工研发有限公司新农药创制与开发国家重点实验室,农药国家工程研究中心,沈阳110021

出　　处：《农药》2025年第1期14-18,共5页Agrochemicals

摘　　要：[目的]Rimisoxafen是FMC公司研发并于2021年获得ISO通用名的除草化合物,主要研究其合成方法和除草活性。[方法]以2,6-二氯苯乙酮为起始原料,经3步反应合成rimisoxafen。[结果]总收率8.3%,纯度99%,目标化合物结构经1H NMR和高分辨质谱确证。室内除草活性测试结果显示,rimisoxafen对阔叶杂草苘麻和百日草具有优异的苗后防治效果,在有效成分为37.5 g a.i./hm^(2)剂量下,防效可达到100%。[Aims]Rimisoxafen was a new herbicide developed by FMC Corporation and achieved ISO common name in 2021.This paper mainly investigated its synthetic methods and herbicidal activity.[Methods]Rimisoxafen was synthesized from 1-(2,6-dichlorophenyl)ethan-1-one in 3 steps.[Results]The overall yield was 8.3%and the purity of the target compound was 99%.The structure of rimisoxafen was confirmed by 1H NMR and HRMS.The laboratory test results showed that rimisoxafen displayed excellent post-emergence herbicidal activity against broadleaf weeds such as Abutilon theophrasti Medic and Zinnia elegans Jacq.,attaining a control efficacy of 100%at 37.5 g/ha.

关 键 词：rimisoxafen 合成 除草活性 

分 类 号：TQ457.2[化学工程—农药化工]