机构地区:[1]十堰市太和医院神经康复科,湖北十堰442000
出 处:《临床误诊误治》2025年第4期77-82,共6页Clinical Misdiagnosis & Mistherapy
基 金:湖北省科学技术厅项目(2022BCE035)。
摘 要:目的探讨糖尿病周围神经病变(DPN)患者采用调理脾胃浅刺短留针法联合温针灸治疗的临床效果。方法选取2020年1月至2023年12月收治的122例DPN患者,采用随机数字表法分为2组,对照组(n=62)给予温针灸疗法,观察组(n=60)在对照组基础上联合调理脾胃浅刺短留针法,治疗后4周后比较2组疗效、多伦多临床评分系统(TCSS)评分、密歇根糖尿病神经病变评分(MDNS)、腓神经和正中神经的感觉神经传导速度(SNCV)和运动神经传导速度(MNCV)值、中医证候积分、2型糖尿病患者生活质量量表(DMQLS)评分、血清超氧化物歧化酶(SOD)和丙二醛(MDA)水平变化以及不良反应发生情况。结果观察组总有效率96.67%(58/60),高于对照组的77.42%(48/62,P<0.05)。治疗后,2组MDNS、TCSS评分、中医证候积分、DMQLS评分以及血清MDA水平较治疗前降低,且观察组降低更明显(P<0.05)。治疗后,2组正中神经和腓神经的SNCV和MNCV值以及血清SOD水平均较治疗前升高,且观察组升高更明显(P<0.05)。2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论采用调理脾胃浅刺短留针法联合温针灸治疗DPN具有较好的效果,能减轻周围神经损伤,抑制氧化应激反应,改善患者生活质量,且治疗安全性较高。Objective To investigate the clinical effect of shallow puncture and short needle retention method for regulating spleen and stomach combined with warm acupuncture and moxibustion in the treatment of diabetic peripheral neuropathy(DPN).Methods A total of 122 DPN patients admitted from January 2020 to December 2023 were divided into two groups by random number table method.The control group(n=62)was given warm acupuncture and moxibustion therapy,and the observation group(n=60)was supplemented with shallow puncture and short needle retention method for regulating spleen and stomach.At 4 weeks after treatment,the therapeutic effect,Toronto Clinical Scoring system(TCSS)score,Michigan Diabetic Neuropathy score(MDNS),sensory nerve conduction velocity(SNCV)and motor nerve conduction velocity(MNCV)values of peroneal nerve and median nerve,traditional Chinese medicine(TCM)syndrome score,Quality of Life Scale for Patients with Type 2 Diabetes Mellitus(DMQLS)score,the changes of serum superoxide dismutase(SOD)and malondialdehyde(MDA)levels and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 96.67%(58/60),which was higher than that of the control group 77.42%(48/62,P<0.05).After treatment,MDNS,TCSS scores,TCM syndrome scores,DMQLS scores and serum MDA level in the two groups were significantly lower than those before treatment,and the decrease was more significant in observation group(P<0.05).After treatment,SNCV and MNCV of median nerve and peroneal nerve as well as serum SOD level in the two groups were significantly higher than those before treatment,and the increase was more significant in observation group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The treatment of DPN with shallow puncture and short needle retention method for regulating spleen and stomach combined with warm acupuncture and moxibustion has a good effect,which can reduce peripheral
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