肌钙蛋白Ⅰ、N末端脑钠肽前体、超敏 C反应蛋白和降钙素原联合检测在急性冠脉综合征诊断中的临床价值  

Clinical Value of Combined Detection of TroponinⅠ、N-terminal pro-brain natriuretic peptide、High-sensitivity C-reactive Protein And Procalcitonin in the Diagnosis of Acute Coronary Syndrome

作　　者：向璐 严翠萍 罗兴荣 于建江 Xiang Lu;Yan Cuiping;Luo XingRong;Yu JianJiang(Yangzhou Hongquan Hospital Laboratory Department,Yangzhou Jiangsu 225200,China)

机构地区：[1]扬州洪泉医院检验科,江苏扬州225200

出　　处：《生命科学仪器》2024年第6期23-25,共3页Life Science Instruments

摘　　要：目的探究在急性冠脉综合征诊断中联合检测肌钙蛋白Ⅰ(cTnⅠ)、N末端脑钠肽前体(NT-proBNP)、超敏C反应蛋白(hs-CRP)和降钙素原(PCT)的价值。方法选择2022年1月至2024年7月期间扬州洪泉医院收治的急性冠脉综合征患者34例,设为观察组;随机选择同期医院健康体检者34名,设为对照组。比较两组cTnⅠ、NT-proBNP、hs-CRP和PCT水平,并分析联合指标检测的诊断效能。结果观察组cTnⅠ、NT-proBNP、hs-CRP、PCT水平均高于对照组(P<0.05)。联合指标诊断急性冠脉综合征的准确度、灵敏度分别为97.06%(66/68)、97.06%(33/34),均高于单独指标检测(P<0.05);联合指标诊断的特异度与单独检测对比(P>0.05)。结论在急性冠脉综合征诊断中联合检测cTnⅠ、NT-proBNP、hs-CRP与PCT的诊断效能更佳,有利于疾病治疗的开展。Objective:To explore the value of combined detection of troponin I(cTnⅠ)、N-terminal pro-brain natriuretic peptide(NT-proBNP)、High-sensitivity c-reactive protein(hs-CRP)and procalcitonin(PCT)in the diagnosis of acute coronary syndrome.Methods:34 patients with acute coronary syndrome admitted to Yangzhou Hongquan Hospital from January 2022 to July 2024 were selected as the observation group.34 healthy people in the same period were randomly selected as the control group.The levels of cTnⅠ、NT-proBNP、hs-CRP and PCT were compared between the two groups,and the diagnostic efficiency of joint index detection was analyzed.Results:the levels of cTnⅠ、NT-proBNP、hs-CRP and PCT in the observation group were higher than those in the control group(P<0.05).The accuracy and sensitivity of combined indexes in the diagnosis of acute coronary syndrome were 97.06%(66/68)and 97.06%(33/34),which were higher than those of single indexes(P<0.05).The specificity of combined diagnosis was compared with that of single detection(P>0.05).Conclusion:Combined detection of cTnⅠ、NT-proBNP、hs-CRP and PCT is more effective in the diagnosis of acute coronary syndrome,which is beneficial to the development of disease treatment.

关 键 词：急性冠脉综合征 肌钙蛋白Ⅰ N末端脑钠肽前体 超敏C反应蛋白 降钙素原 诊断效能 

分 类 号：R541.4[医药卫生—心血管疾病]