腹腔镜完全腹膜外疝修补术对腹股沟疝患者炎症介质与氧化应激及疼痛介质的影响  

Effects of Laparoscopic Total Extraperitoneal Hernia Repair on Inflammatory Mediators、Oxidative Stress And Pain Mediators in Patients with Inguinal Hernia

作　　者：许成裘 蔡观河 王扩杰 曹展祯 严聪[1] Xu Chengqiu;Cai Guanhe;Wang Kuojie;Cao Zhanzhen;Yan Cong(Department of General Surgery,Zhanjiang Central People's Hospital,Zhanjiang Guangdong 524033,China)

机构地区：[1]湛江中心人民医院普外三科,广东湛江524033

出　　处：《生命科学仪器》2024年第6期14-16,共3页Life Science Instruments

摘　　要：目的探讨采用腹腔镜完全腹膜外疝修补术(TEP)治疗腹股沟疝的效果及对炎症介质、氧化应激与疼痛介质的影响。方法选择80例2022年1月至2023年12月在湛江中心人民医院接受手术治疗的腹股沟疝患者,采用随机数表法分为开放组和TEP组,每组40例。开放组接受开放式疝修补术,TEP组接受TEP手术。观察对比两组总体效果。结果TEP组手术指标、术后并发症发生率优于开放组,手术后1 d炎症介质、氧化应激、疼痛介质均优于开放组(P<0.05)。结论与开放式疝修补手术相比,TEP具有并发症少、创伤小、康复快的优点,且对炎症反应、氧化应激及痛觉的影响均更小。Objective:To explore the effect of laparoscopic total extraperitoneal hernia repair(TEP)on inguinal hernia and its influence on inflammatory mediators,oxidative stress and pain mediators.Methods:Eighty patients with inguinal hernia who underwent surgical treatment in Zhanjiang Central People's Hospital from January 2022 to December 2023 were randomly divided into open group and TEP group,with 40 cases in each group.Open group received open hernia repair and TEP group received TEP operation.Observe and compare the overall effect of the two groups.Results:The operative indexes and postoperative complications in TEP group were better than those in open group、and the inflammatory mediators、oxidative stress and pain mediators were better than those in open group 1 day after operation(P<0.05).Conclusion:Compared with open hernia repair,TEP has the advantages of less complications,less trauma and faster recovery,and has less influence on inflammatory reaction,oxidative stress and pain.

关 键 词：腹股沟疝 腹腔镜完全腹膜外疝修补术 炎症介质 氧化应激 疼痛介质 

分 类 号：R656.21[医药卫生—外科学]