抗生素合理应用情况分析与循证药学的应用价值  

To Study the Application Value of Rational Application of Antibiotics And Evidence-based Pharmacy

作　　者：胡明芳 孟欣 杨轶 Hu Mingfang;Meng Xin;Yang Yi(Beijing Fengtai District Hospital of Traditional Chinese Medicine(Beijing Fengtai District Nanyuan Hospital),Beijing 100076,China)

机构地区：[1]北京市丰台区中医医院(北京市丰台区南苑医院),北京100076

出　　处：《生命科学仪器》2024年第6期127-129,共3页Life Science Instruments

摘　　要：目的探讨循证药学(EBP)对促进抗生素合理应用的价值。方法选择北京市丰台区中医医院(北京市丰台区南苑医院)2023年1月至6月开展EBP管理前随机抽检的2000张抗生素处方、2023年7月至12月开展EBP管理后随机抽检的2000张抗生素处方作为研究对象。对比开展EBP管理前后医院抗生素合理应用情况。结果开展EBP管理后,医院抗生素合理用药情况得到显著提升,抽检不合理处方率、抗生素联合用药率、预防性用药率均较开展EBP管理前显著下降(P<0.05)。开展EBP管理后,医师对抗菌药物的认知明显好于开展前(P<0.05)。开展EBP管理后,统计发现用药不良反应率仅为1.10%,明显低于开展EBP管理前的5.70%(P<0.05)。结论开展EBP管理对促进抗生素合理应用、提高医师对抗菌药物的认知,从而减少用药不良反应具有积极意义。Objective:To explore the value of evidence-based pharmacy(EBP)in promoting the rational use of antibiotics.Methods:2000 antibiotic prescriptions randomly selected from Beijing Fengtai Traditional Chinese Medicine Hospital(Beijing Fengtai Nanyuan Hospital)before EBP management from January to June 2023 and 2000 antibiotic prescriptions randomly selected after EBP management from July to December 2023 were selected as the research objects.To compare the rational use of antibiotics in hospitals before and after EBP management.Results:After EBP management,the rational use of antibiotics in the hospital was significantly improved,and the rate of irrational prescription,combined use of antibiotics and preventive use were significantly lower than before EBP management(P<0.05).After EBP management,doctors'knowledge of antibacterial drugs was significantly better than before(P<0.05).After EBP management,it was found that the adverse drug reaction rate was only 1.10%,which was significantly lower than 5.70%before EBP management(P<0.05).Conclusion:EBP management is of positive significance to promote the rational use of antibiotics,improve doctors'knowledge of antibacterial drugs,and thus reduce adverse drug reactions.

关 键 词：循证药学管理 抗生素合理应用 预防性用药 用药不良反应 

分 类 号：R978.1[医药卫生—药品]