出 处:《中华地方病学杂志》2024年第11期891-896,共6页Chinese Journal of Endemiology
基 金:河南省医学科技攻关计划(LHGJ20220163)
摘 要:目的了解河南省适碘地区重点人群的碘营养状况,为适时采取针对性防治措施和科学制定适碘地区补碘策略提供依据。方法2022年3-9月,采用横断面调查方法,在河南省13个省辖市的60个适碘县(市、区),将每个县(市、区)辖内水碘中位数为40~100μg/L的行政村按水碘值分层(40~49、50~59、60~69、70~79、80~89、90~100μg/L),每个水碘层抽取1个行政村,每个行政村抽取8~10岁非寄宿学生40名(年龄均衡、男女各半)和孕妇20名;分别采集儿童、孕妇家庭食用盐盐样和随意1次尿样,检测盐碘、尿碘含量;并对儿童进行甲状腺检查。结果共采集8~10岁儿童家庭食用盐盐样12203份,盐碘中位数为24.5 mg/kg,碘盐覆盖率为85.3%(10414/12203),合格碘盐食用率为77.1%(9406/12203);采集孕妇家庭食用盐盐样3999份,盐碘中位数为24.0 mg/kg,碘盐覆盖率为84.2%(3366/3999),合格碘盐食用率为74.5%(2981/3999)。共采集8~10岁儿童尿样12241份,尿碘中位数为290.4μg/L;采集孕妇尿样4084份,尿碘中位数为233.0μg/L。检查儿童甲状腺11971例,甲状腺肿大率为2.1%(257/11971)。按水碘含量划分,40~59、60~79、80~100μg/L水碘范围组儿童尿碘中位数分别为269.7、298.0、308.0μg/L,组间比较差异有统计学意义(H=67.32,P<0.001);儿童甲状腺肿大率分别为2.2%(100/4603)、2.1%(80/3733)、2.1%(77/3635),组间比较差异无统计学意义(χ^(2)=0.03,P=0.986);孕妇尿碘中位数分别为225.4、243.1、234.4μg/L,组间比较差异有统计学意义(H=10.96,P=0.004)。结论河南省适碘地区儿童碘营养处于超适宜量水平,孕妇碘营养处于碘适宜水平,建议在维持目前防治措施基础上加强监测,根据人群碘营养变化情况及时调整防治措施。Objective To investigate the iodine nutritional status of key populations in iodine adequate areas in Henan Province,and provide a basis for timely adoption of targeted prevention and control measures and scientific formulation of iodine supplementation strategies in iodine adequate areas.Methods From March to September 2022,a cross-sectional survey was conducted in 60 iodine adequate counties(cities,districts)in 13 provincial-level cities in Henan Province.Administrative villages with a median water iodine level of 40-100μg/L within each county(city,district)were stratified by water iodine value(40-49,50-59,60-69,70-79,80-89,90-100μg/L).One administrative village was selected from each water iodine layer,and 40 non boarding students aged 8-10 years old(age balanced,half male and half female)and 20 pregnant women were selected from each administrative village to collect their household edible salt samples and once random urine sample for test salt iodine and urinary iodine contents;and the thyroid volume of children was measured.Results A total of 12203 samples of household edible salt were collected from children aged 8-10 years old,with a median salt iodine of 24.5 mg/kg,the iodized salt coverage rate was 85.3%(10414/12203),and the qualified iodized salt consumption rate was 77.1%(9406/12203).A total of 3999 samples of household edible salt were collected from pregnant women,with a median salt iodine of 24.0 mg/kg,the iodized salt coverage rate was 84.2%(3366/3999),and the qualified iodized salt consumption rate was 74.5%(2981/3999).A total of 12241 urine samples from children aged 8-10 years old were collected,with a median urinary iodine of 290.4μg/L.A total of 4084 urine samples from pregnant women were collectedd,with a median urinary iodine of 233.0μg/L.The thyroid volume of 11971 children was examined,and the rate of goiter was 2.1%(257/11971).Stratified by water iodine content,the median urinary iodine levels of children in 40-59,60-79,and 80-100μg/L water iodine groups were 269.7,298.0 and 308.0μg
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