酶联免疫吸附试验法与胶体金试验在人类免疫缺陷病毒抗体检测中的效果分析  

Effect analysis of enzyme-linked immunosorbent assay and colloidal gold test in human immunodeficiency virus antibody detection

作　　者：郭艳飞 GUO Yan-Fei(Wafangdian Center for Disease Control and Prevention,Dalian 116300,China)

机构地区：[1]瓦房店市疾病预防控制中心,大连116300

出　　处：《实验室检测》2024年第10期101-103,共3页Laboratory Testing

摘　　要：目的分析酶联免疫吸附试验法与胶体金试验在人类免疫缺陷病毒(Human Immunodeficiency Virus,HIV)抗体检测中的效果。方法选择2022年1月到2024年1月期间本单位哨点监测和艾滋病确诊患者接触人群50例为观察目标,分别接受酶联免疫吸附试验法、胶体金试验检测,分析患者检测结果的差异。结果50例重点人群中,最终确诊36例、阴性14例,该结果为本次研究的黄金标准。酶联免疫吸附试验法的诊断效果显著优于胶体金试验检测结果,差异具有统计学意义(P<0.05)。结论酶联免疫吸附试验法在HIV抗体检测中的效果显著优于与胶体金试验检测,值得作为首选检测方法。Objective To analyze the effectiveness of enzyme-linked immunosorbent assay(ELISA)and colloidal gold test in the detection of human immunodeficiency virus(HIV)antibodies.Methods From January 2022 to January 2024,50 cases of sentinel surveillance and contact population of confirmed AIDS patients in our unit were selected as the observation target,and they were detected by ELISA and colloidal gold test respectively,and the difference of patients’detection results was analyzed.Results Among the 50 key populations,36 were ultimately diagnosed and 14 were negative,which is the gold standard for this study.The diagnostic effect of enzyme-linked immunosorbent assay is significantly better than that of colloidal gold assay,and the difference is statistically significant(P<0.05).Conclusion The enzyme-linked immunosorbent assay(ELISA)is significantly more effective in HIV antibody detection than colloidal gold assay,and is worthy of being the preferred detection method.

关 键 词：艾滋病 艾滋病病毒 酶联免疫吸附试验法 胶体金试验 诊断有效性 

分 类 号：R446.6[医药卫生—诊断学] R512.91[医药卫生—临床医学]