股神经联合股外侧皮神经阻滞麻醉对老年危重症患者下肢骨折手术氧化应激与术后恢复的影响  

Effect of Anesthesia with Combined Femoral Nerve and Lateral Femoral Cutaneous Nerve Block on Oxidative Stress And Postoperative Recovery in Lower Extremity Fracture Surgery in Elderly Critically Ill Patients

作　　者：许君 曹智 Xu Jun;Cao Zhi(The Fourth Affiliated Hospital of the Nanjing Medical University,Nanjing Jiangsu 210000,China)

机构地区：[1]南京医科大学第四附属医院,江苏南京210000

出　　处：《生命科学仪器》2024年第5期64-66,69,共4页Life Science Instruments

摘　　要：目的 研究股神经联合股外侧皮神经阻滞麻醉对老年危重症患者下肢骨折手术氧化应激与术后恢复的影响。方法 选择2022年6月至2023年6月期间在南京医科大学第四附属医院接受手术治疗的老年危重症下肢骨折患者60例,随机分为对照组(采用腰硬联合麻醉)和研究组(采用股神经联合股外侧皮神经阻滞麻醉),各30例。比较两组各项临床指标。结果 相比对照组,研究组T1、T2、T3的血流动力学指标波动幅度更低,SOD水平均更高,MDA与NE水平均更低,P<0.05。与对照组相比,研究组运动阻滞持续时长更短,术后1 d内不同时间点其认知功能评分均更高,P<0.05。研究组不良反应发生率较对照组更低,对手术麻醉的满意度较对照组更高,P<0.05。结论 在老年危重症患者下肢骨折手术中应用股神经联合股外侧皮神经阻滞麻醉可稳定血流动力学,缩短运动阻滞持续时间,加快认知功能恢复,减少不良反应,提高麻醉满意度。Objective:To study the effect of femoral nerve combined with lateral femoral cutaneous nerve block anesthesia on oxidative stress and postoperative recovery of lower limb fracture in elderly critically ill patients.Methods:From June 2022 to June 2023,60 elderly critically ill patients with lower limb fractures were selected and randomly divided into control group(using combined spinal-epidural anesthesia)and study group(using femoral nerve combined with lateral femoral cutaneous nerve block anesthesia),with 30 cases in each group.The clinical indexes of the two groups were compared.Results:Compared with the control group,the fluctuation range of hemodynamic indexes of T1、T2 and T3 in the study group was lower,the SOD level was higher,and the MDA and NE levels were lower,P<0.05.Compared with the control group,the duration of motor block in the study group was shorter,and its cognitive function scores were higher at different time points within 1 day after operation,P<0.05.The incidence of adverse reactions in the study group was lower than that in the control group,and the satisfaction with surgical anesthesia was higher than that in the control group,P<0.05.Conclusion:Femoral nerve combined with lateral femoral cutaneous nerve block anesthesia can stabilize hemodynamics,shorten the duration of motor block,accelerate the recovery of cognitive function,reduce adverse reactions and improve anesthesia satisfaction.

关 键 词：股神经联合股外侧皮神经阻滞麻醉 氧化应激 运动阻滞时间 不良反应 

分 类 号：R614[医药卫生—麻醉学]