超声造影及彩色多普勒超声联合剪切波弹性成像检测对鼻咽癌患者放疗后颈动脉损伤的诊断价值  

Value of Contrast-Enhanced Ultrasonography And Color Doppler Ultrasonography Combined with Shear-wave Elastography in Diagnosis of Carotid Artery Injury in Patients with Nasopharyngeal Carcinoma after Radiotherapy

作　　者：李小霞 肖雨雄[1] 邓芸[1] 梁爱群[1] Li Xiaoxia;Xiao Yuxiong;Deng Yun;Liang AiQun(North Guangdong People's Hospital of Shaoguan City,Shaoguan Guangdong 512026,China)

机构地区：[1]韶关市粤北人民医院,广东韶关512026

出　　处：《生命科学仪器》2024年第5期33-36,共4页Life Science Instruments

基　　金：韶关市卫生健康科研项目,编号:Y22104

摘　　要：目的 分析超声造影及彩色多普勒超声联合剪切波弹性成像检测对鼻咽癌患者放疗后颈动脉损伤的诊断价值。方法 选择2022年1月至2023年12月韶关市粤北人民医院收治的经组织病理检查确诊的100例鼻咽癌患者,将其中接受放疗的50例患者作为观察组,将新确诊未接受放疗的50例患者作为对照组。对比两组患者的超声造影、彩色多普勒、剪切波弹性成像检测参数,采用受试者工作曲线(ROC)分析超声造影及彩色多普勒超声联合剪切波弹性成像检测诊断鼻咽癌患者放疗后颈动脉损伤的临床价值。结果 观察组颈动脉内-中膜厚度、阻力指数及其狭窄程度均高于对照组,P<0.05。观察组颈动脉舒张末期血流速度和收缩期峰值流速均低于对照组,P<0.05。观察组杨氏模量最大值、最小值、平均值均高于对照组,P<0.05。彩色多普勒超声、剪切波弹性成像、超声造影及三者联合诊断鼻咽癌患者放疗后颈动脉损伤的敏感度、特异度均高于单独应用,P<0.05。结论 超声造影、彩色多普勒超声、剪切波弹性成像联合诊断鼻咽癌患者放疗后颈动脉损伤的效能高于单独应用。Objective:Toanalyze the diagnostic value of contrast-enhanced ultrasound and color Doppler ultrasound combined with shear wave elastography in carotid artery injury of nasopharyngeal carcinoma patients after radiotherapy.Methods:From January 2022 to December 2023,100 patients with nasopharyngeal carcinoma diagnosed by histopathological examination in Shaoguan Yuebei People's Hospital were selected.Among them,50 patients received radiotherapy as the observation group,and 50 patients newly diagnosed without radiotherapy as the control group.The parameters of contrast-enhanced ultrasound,color Doppler ultrasound and shear-wave elastography were compared between the two groups,and the clinical value of contrast-enhanced ultrasound and color Doppler ultrasound combined with shear-wave elastography in the diagnosis of carotid artery injury in nasopharyngeal carcinoma patients after radiotherapy was analyzed by receiver working curve(ROC).Results:The carotid intimamedia thickness,resistance index and stenosis degree in the observation group were higher than those in the control group,P<0.05.The end-diastolic velocity and peak systolic velocity of carotid artery in observation group were lower than those in control group,P<0.05.The maximum、minimum and average values of Young's modulus in the observation group were higher than those in the control group,P<0.05.The sensitivity and specificity of color Doppler ultrasound,shear wave elastography,contrast-enhanced ultrasound and their combination in the diagnosis of carotid artery injury in nasopharyngeal carcinoma patients after radiotherapy were higher than those of single application,P<0.05.Conclusion:Contrast-enhanced ultrasound,color Doppler ultrasound and shear wave elastography are more effective in the diagnosis of carotid artery injury in patients with nasopharyngeal carcinoma after radiotherapy than single application.

关 键 词：超声造影 彩色多普勒 剪切波弹性成像 鼻咽癌 放疗 颈动脉损伤 

分 类 号：R445.1[医药卫生—影像医学与核医学]