脑功能与结构磁共振成像在慢性阻塞性肺疾病中的应用研究进展  

Application of functional and structural magnetic resonance imaging of brain in chronic obstructive pulmonary disease:research progress

作　　者：于清扬 刘士远 YU Qingyang;LIU Shiyuan(Department of Radiology,The Second Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200003,China)

机构地区：[1]海军军医大学(第二军医大学)第二附属医院医学影像科,上海200003

出　　处：《海军军医大学学报》2025年第2期234-238,共5页Academic Journal of Naval Medical University

基　　金：国家自然科学基金重点项目(81930049).

摘　　要：慢性阻塞性肺疾病(COPD)是一种最常见的慢性肺疾病,其主要特征是慢性不可逆性气道受阻。患者长期气流受限引起大脑供氧量减少,易引起大脑功能与结构的一系列改变。近年来很多MRI技术应用于COPD患者的研究。本文主要从静息态功能磁共振成像、基于体素的形态测量及弥散张量成像3个方面,对基于脑功能与结构成像技术在COPD中的研究进展进行综述。Chronic obstructive pulmonary disease(COPD)is one of the most common chronic lung diseases,which is characterized by chronic irreversible airway obstruction.Chronic airflow restriction causes a decrease in oxygen supply to the brain,which inevitably leads to a series of changes in brain function and structure.In recent years,many magnetic resonance imaging(MRI)technology has been applied to explore the brain function and structure of COPD.Resting-state functional MRI,voxel-based morphometry,and diffusion tensor imaging are reviewed in this article to discuss the recent research progress of brain function and structure imaging study in COPD.

关 键 词：慢性阻塞性肺疾病 静息态功能磁共振成像 基于体素的形态测量 弥散张量成像 

分 类 号：R563.9[医药卫生—呼吸系统] R445.2[医药卫生—内科学]