Effects of transcutaneous electrical point stimulation on awakening,cognition,and immune function in patients undergoing laparoscopic cholecystectomy  

经皮穴位电刺激对腹腔镜胆囊摘除术患者苏醒、认知及免疫功能的影响

作　　者：XU Xuefen CHEN Meihua 徐雪芬;陈梅花(Suzhou Hospital of Traditional Chinese Medicine,Jiangsu Province,Suzhou 215000,China)

机构地区：[1]Suzhou Hospital of Traditional Chinese Medicine,Jiangsu Province,Suzhou 215000,China

出　　处：《Journal of Acupuncture and Tuina Science》2025年第1期43-48,共6页针灸推拿医学(英文版)

摘　　要：Objective:To observe the effects of transcutaneous electrical point stimulation(TEPS)on awakening,cognition,and immune function in patients undergoing laparoscopic cholecystectomy(LC)under general anesthesia.Methods:Ninety patients undergoing LC under general anesthesia were selected as the study subjects and were divided into a control group and an observation group according to the random number table method,with 45 cases in each group.The control group was operated with conventional general anesthesia.The observation group was treated with the same anesthesia as the control group,and TEPS was performed at Hegu(LI4),Zusanli(ST36),and Neiguan(PC6)before the induction of anesthesia until the completion of the operation.The quality of postoperative awakening,hemodynamic indicators,cognitive function,and immune function of patients in the two groups were compared,and the occurrence of adverse reactions was recorded.Results:The time of recovery of spontaneous breathing and extubation time of the observation group were shorter than those of the control group(P<0.05);there was no statistically significant difference in the heart rate(HR)and mean arterial pressure(MAP)between the two groups at the moment before the induction of anesthesia(T1)(P>0.05);at the moment of extubation(T2)and 5 min after extubation(T3),the HR and MAP of patients in both groups were higher than those at T1(P<0.05),and those of the observation group were lower than those of the control group(P<0.05).Preoperatively,there was no statistically significant difference in the Montreal cognitive assessment scale(MoCA)score between the two groups(P>0.05);3 d postoperatively,the MoCA score of the two groups decreased and was higher in the observation group than in the control group(P<0.05).Preoperatively,there was no statistical difference in the comparison of CD4^(+),CD8^(+),and CD4^(+)/CD8^(+) between the two groups(P>0.05);3 d postoperatively,the above indicators decreased in both groups(P<0.05)and were higher in the observation group than in the cont目的:观察经皮穴位电刺激(TEPS)对全麻腹腔镜胆囊摘除术(LC)患者苏醒、认知及免疫功能的影响。方法:选取全麻腹腔镜胆囊摘除术的90例患者为研究对象,按照随机数字表法将其为对照组和观察组,每组45例。对照组行常规全麻手术,观察组采用与对照组相同的麻醉方式,在麻醉诱导前于合谷、足三里和内关行TEPS直至手术完成。比较两组患者术后苏醒质量、血流动力学指标、认知功能及免疫功能,并记录不良反应发生情况。结果:观察组恢复自主呼吸时间、拔管时间均短于对照组(P<0.05);麻醉诱导前(T1)时刻,两组患者心率(HR)及平均动脉压(MAP)对比无统计学差异(P>0.05);拔管时(T2)、拔管5 min后(T3)时刻,两组患者HR及MAP均较T1时刻升高(P<0.05),观察组低于对照组(P<0.05)。术前,两组患者蒙特利尔认知评估量表(MoCA)评分无统计学差异(P>0.05);术后3 d,两组患者MoCA评分均下降,观察组高于对照组(P<0.05)。术前,两组患者CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+)比较无统计学差异(P>0.05);术后3 d,两组上述指标均下降(P<0.05),观察组高于对照组(P<0.05)。两组患者不良反应总发生率无统计学差异(P>0.05)。结论:应用合谷、足三里和内关TEPS配合全麻可提高LC患者术后苏醒质量,促进血流动力学稳定,改善认知功能及免疫功能,且安全性良好。

关 键 词：Point Therapy Point Hegu(LI4) Point Zusanli(ST36) Point Neiguan(PC6) Transcutaneous Electrical Stimulation Laparoscopic Cholecystectomy Postoperative Complications 

分 类 号：R246.2[医药卫生—针灸推拿学]