Observation of the clinical efficacy of treating allergic rhinoconjunctivitis with acupuncture and its effects on inflammatory cells  

观察针刺治疗过敏性鼻结膜炎的临床疗效及其对炎性细胞的影响

作　　者：HU Long PENG Ye XU Huilei 胡龙;彭烨;许慧蕾(Zhejiang Lücheng Cardiovascular Diseases Hospital,Hangzhou 310000,China)

机构地区：[1]Zhejiang Lücheng Cardiovascular Diseases Hospital,Hangzhou 310000,China

出　　处：《Journal of Acupuncture and Tuina Science》2025年第1期95-100,共6页针灸推拿医学(英文版)

基　　金：approved by the Medical Ethics Committee of Zhejiang Lücheng Cardiovascular Diseases Hospital(Approval No.ZHKY202201008)。

摘　　要：Objective:To discuss the efficacy of treating allergic rhinoconjunctivitis(ARC)with intranasal acupuncture at Neiyingxiang(EX-HN9)and Biqiu(Extra)points and the effects on inflammatory cells.Methods:A total of 207 ARC patients were recruited and divided into an observation group(104 cases)and a control group(103 cases)using the random number table method.The control group was prescribed desloratadine dispersible tablets and azelastine hydrochloride eye drops for 1 week,and the observation group was given additional acupuncture at bilateral Neiyingxiang(EX-HN9)and Biqiu(Extra)points,once daily consecutively over 1 week.The clinical efficacy was compared between the two groups when the treatment finished.Before and after treatment,both groups were scored using the rhinoconjunctivitis quality of life questionnaire(RQLQ),and the levels of blood eosinophils(EOS)and interleukin(IL)-17 were detected.The cured cases were observed for recurrence rate at the 6-month follow-up.Results:The observation group had more significant clinical efficacy than the control group(P<0.05).After treatment,The RQLQ score declined in both groups(P<0.05)and was lower in the observation group than in the control group(P<0.05).After the intervention,the levels of blood EOS and IL-17 dropped in the two groups and were lower in the observation group than in the control group(P<0.05).At the 6-month follow-up among the cured cases,a lower recurrence rate was found in the observation group compared to the control group(P<0.05).Conclusion:Based on conventional medications,acupuncture at Neiyingxiang(EX-HN9)and Biqiu(Extra)points can notably enhance the clinical efficacy in treating ARC patients,reducing the inflammatory cells and lowering the recurrence rate.目的:探讨鼻内针刺内迎香和鼻丘穴治疗变应性鼻结膜炎患者的疗效及其对炎性细胞的影响。方法:选取变应性鼻结膜炎患者207例,按随机数字表法分为观察组104例和对照组103例。对照组予地氯雷他定分散片联合盐酸氮卓斯汀滴眼液治疗1周,观察组在对照组基础上加针刺双侧内迎香及鼻丘穴,每日1次,连续治疗1周。治疗结束后比较两组临床疗效。于治疗前后进行鼻结膜炎生活质量问卷(RQLQ)评分,行血嗜酸性粒细胞(EOS)和白细胞介素(IL)-17水平检测。对痊愈患者随访6个月观察复发率。结果:观察组临床疗效高于对照组,组间差异有统计学意义(P<0.05)。治疗后,两组RQLQ评分均较治疗前下降(P<0.05),且观察组评分低于对照组(P<0.05)。治疗后,两组血EOS和IL-17水平均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05)。对痊愈患者随访6个月,观察组复发率低于对照组,组间差异有统计学意义(P<0.05)。结论:常规药物治疗基础上加针刺内迎香和鼻丘穴可明显提高变应性鼻结膜炎患者的临床疗效,减少炎性细胞,降低复发率。

关 键 词：Acupuncture Therapy Acupuncture Medication Combined Rhinitis Allergic Conjunctivitis Allergic EOSINOPHILS Quality of Life 

分 类 号：R246.8[医药卫生—针灸推拿学]