独活中2个新的香豆素类化合物  

Two new coumarin compounds from Angelica biserrata

作　　者：武佳程 赵邯涛 鄢俸蝶 陈前锋[1,2] WU Jia-cheng;ZHAO Han-tao;YAN Feng-die;CHEN Qian-feng(School of Pharmaceutical Sciences,Southwest University,Chongqing 400715,China;The MOE Engineering Research Center of Coptis Development&Utilization,Southwest University,Chongqing 400715,China)

机构地区：[1]西南大学药学院,重庆400715 [2]西南大学黄连开发与利用教育部工程研究中心,重庆400715

出　　处：《药学学报》2025年第1期201-204,共4页Acta Pharmaceutica Sinica

基　　金：重庆市技术创新与应用发展专项(CSTB2024TIAD-GPX0022)。

摘　　要：利用硅胶、Sephadex LH-20和半制备高效液相等色谱方法,对独活(Angelica biserrata)75%乙醇提取物的二氯甲烷部位进行分离纯化,从独活二氯甲烷部位中分离得到2个新的香豆素苷。综合运用现代波谱学手段分别鉴定为angelmanetin A(1)和angelmanetin B(2)。Two new coumarin glycosides were isolated and purified from the dichloromethane fraction of Angelica biserrata 75%ethanol extract using silica gel,Sephadex LH-20 column chromatography,and semi-preparative high-performance liquid chromatography.Through the comprehensive use of modern spectroscopic methods,their structures were identified as angelmanetin A(1)and angelmanetin B(2),respectively.

关 键 词：独活 化学成分 香豆素 

分 类 号：R284[医药卫生—中药学]