穿山龙、刘寄奴、徐长卿治疗免疫毒性经验——仝小林三味小方撷萃  

Experience of using pangolin scales,diverse wormwood herb and paniculate swallowwort root in the treatment of immunotoxicity-A three-ingredient prescription by Professor Tong Xiaolin

作　　者：刘珂 罗宝灵 张琳琳 于晓彤[1] 杜林 LIU Ke;LUO Baoling;ZHANG Linlin;YU Xiaotong;DU Lin(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Changchun University of Chinese Medicine,Changchun 130117,China;Taoranting Community Health Service Center,Xicheng District,Beijing 100054,China;Shenzhen Hospital of Guangzhou University of Chinese Medicine,Shenzhen 518000,China)

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]长春中医药大学,长春130117 [3]北京市陶然亭社区卫生服务中心,北京100054 [4]广州中医药大学深圳医院<福田>,广东深圳518000

出　　处：《吉林中医药》2025年第2期162-165,共4页Jilin Journal of Chinese Medicine

基　　金：深圳市“医疗卫生三名工程”仝小林院士中医代谢病团队项目(SZZYSM202202010);中国中医科学院科技创新工程重大攻关项目(CI2021A01611)。

摘　　要：自身免疫性疾病常伴有相关抗体或炎症水平的升高,仝小林基于多年临证经验,认为这类疾病可使机体发展成炎毒、热毒、血毒等状态,故统称为免疫毒性,临床常表现为疾病反复发作,并伴有免疫相关抗体的升高。仝小林将其归属为“脏腑风湿”的论治范畴,并认为“风湿内伏,瘀毒交错”是其核心病机,治疗原则应以祛风除湿,调平免疫为主。结合态靶辨治理论,精心化裁穿山龙、刘寄奴、徐长卿作为三味基础小方,用以祛风除湿,解毒通络,旨在改善免疫失调内环境,入汤剂时,临床常用剂量分别为穿山龙15~90g,刘寄奴9~15g,徐长卿9~15g,同时配合相应调态方和打靶药使用,取得了良好的临床疗效。Autoimmune diseases are often accompanied by elevated levels of related antibodies or inflammation.Based on years of clinical experience,Academician Tong Xiaolin believes that this type of diseases can cause the body to develop into a state of inflammation toxicity,heat toxicity,and/or blood toxicity,etc.Therefore,these states are collectively referred to as immunotoxicity,which is clinically manifested as recurrent disease attacks accompanied by elevated levels of immune-related antibodies.Academician Tong classifies it as the category of"syndrome of wind-damp in viscera"for its syndrome differentiation and treatment and holds that its core pathogenesis is"internal accumulation of wind-damp and the interweaving of blood stasis and toxin",with its treatment principle mainly focusing on dispelling wind and dampness,and regulating the immune system.Combined with the theory of statetarget differentiation and treatment,pangolin scales,diverse wormwood herb and paniculate swallowwort root are meticulously prescribed in a basic formula to dispel wind and dampness,detoxify and unblock collaterals,aiming to improve the internal environment of immune disorders.When used in decoctions,the commonly used clinical dosages are 15-90 g,9-15 g,and 9-15 g,respectively.They are also used together with corresponding state-regulating formulas and target drugs,and significant clinical effects have been achieved.

关 键 词：穿山龙 刘寄奴 徐长卿 免疫毒性 

分 类 号：R283[医药卫生—中药学]