474例COVID-19患者临床特征回顾性分析  

A retrospective analysis on the clinical characteristics of 474 patients with COVID-19

作　　者：胡少丹[1] 崔英子[1] 杨薇[1] 曹政华 李晓红 仕丽[1] HU Shaodan;CUI Yingzi;YANG Wei;CAO Zhenghua;LI Xiaohong;SHI Li(Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China;Changchun University of Chinese Medicine,Changchun 130117,China;Changchun Infectious Disease Hospital,Changchun 130123,China)

机构地区：[1]长春中医药大学附属医院,长春130021 [2]长春中医药大学,长春130117 [3]长春市传染病院,长春130123

出　　处：《吉林中医药》2025年第2期177-181,共5页Jilin Journal of Chinese Medicine

基　　金：吉林省科技发展计划项目(20230203189SF,20230203078SF);吉林省中医药管理局项目(2022219)。

摘　　要：目的回顾性分析长春市474例奥密克戎变异病毒感染的COVID-19患者的临床特征。方法本研究采用横断面研究方法收集2022年3月—2022年4月于长春中医药大学附属医院住院并感染奥密克戎变异病毒感染的COVID-19患者的病例资料,包括性别,年龄,BMI,基础疾病,相关危险因素等,并对出院患者在6个月后进行电话随访,总结新冠后遗症的出现的比例及伴随症状,总结和分析奥密克戎变异病毒感染的COVID-19患者的临床特征。结果本研究患者男女比例相近,以中青年为主,聚集性发病达到40.51%,疫苗接种率可达到92.62%;合并基础疾病前三的为高血压病、冠心病和脂肪肝,危险因素与BMI、年龄和高血压相关;临床症状以发热、身疼痛和有痰相关,中医证型以肺经郁火证为主;转阴时间为(10.57±5.47)d,中位数为10 d,住院时长为(15.04±6.67)d,中位数为14 d;随访成功中新冠后遗症的患病率为9.64%,以乏力为主。结论474例奥密克戎变异病毒感染的COVID-19患者的发病人群以中青年为主,中医证型以肺经郁火证为主,治疗中要时时顾护阴液与心脏,对疾病后期更应关注患者的身心健康。Objective To retrospectively analyze the clinical characteristics of 474 COVID-19 patients infected with the Omicron variant in Changchun.Methods This study used a cross-sectional approach to collect case data of COVID-19 patients infected with the Omicron variant who were hospitalized at the Affiliated Hospital of Changchun University of Chinese Medicine from March 2022 to April 2022.The data included their gender,age,BMI,underlying diseases,and related risk factors.A telephone follow-up was conducted six months after discharge to summarize the incidence and accompanying symptoms of the post-COVID-19 sequelae in them.The clinical characteristics of COVID-19 patients infected with the Omicron variant were summarized and analyzed.Results The study found a similar gender ratio among the study participants,with a predominance of young and middle-aged patients.Clustered outbreaks accounted for 40.51%,and their vaccination rate reached 92.62%.The top three comorbidities were hypertension,coronary heart disease,and fatty liver,with risk factors related to BMI,age,and hypertension.Clinical symptoms mainly included fever,body pain,and phlegm,with the main TCM syndrome featuring fire stagnation in the lung meridian.Their duration to test negative was(10.57±5.47)days,with a median of 10 days,and their duration of hospital stay was(15.04±6.67)days,with a median of 14 days.The incidence of post-COVID-19 sequelae among those successfully followed-up patients was 9.64%,with fatigue being the main symptom.Conclusion Among the 474 COVID-19 patients infected with the Omicron variant,the majority are the young and middle-aged,with the main TCM syndrome of fire stagnation in the lung meridian.During treatment,it is important to attend the yin fluid and the heart,and in the later stage of the disease,more attention should be paid to the physical and mental health of patients.

关 键 词：新冠肺炎 奥密克戎 真实世界 回顾性分析 随访 

分 类 号：R255.9[医药卫生—中医内科学]