纤维素催化转化制乙酰丙酸研究进展  

Research advances of cellulose conversion to levulinic acid

作　　者：张浩楠 李晨[1] 王硕[1] 王祺元 李恒 杨英[1] ZHANG Haonan;LI Chen;WANG Shuuo;WANG Qiyuan;LI Heng;YANG Ying(School of Chemical Engineering and Environment,China University of Petroleum,Beijing 102249,China)

机构地区：[1]中国石油大学(北京)化学工程与环境学院,北京102249

出　　处：《化学研究》2025年第1期2-16,共15页Chemical Research

基　　金：国家自然科学基金资助项目(U2330105);国家重点研发课题(2022YFB1105100)。

摘　　要：乙酰丙酸作为最具潜力的生物质平台化合物之一,被广泛应用于生产香料、化妆品、医药、农药和杀菌剂等,是重要的化工原料。其中,采用纤维素直接转化制备乙酰丙酸,可显著减少对化石能源的使用,降低成本,有助于推动可持续发展。本文系统综述了纤维素催化转化制乙酰丙酸的反应路径、工艺方法、催化体系以及催化性能的影响因素。简要概述多步法与一步法工艺的发展现状,并深入探讨了工艺条件(如温度、溶剂等)对产物收率的影响。此外,总结了纤维素制备乙酰丙酸的固体酸催化剂的发展现状,并着重评述了活性位调控和孔结构设计方面对催化剂活性的影响。基于此,对纤维素制乙酰丙酸催化剂的设计、制备、工艺发展以及纤维素原料等进行了展望,旨在为后续研究提供参考。Levulinic acidrecognized as a promising compound within the biomass platform,serves as a crucial chemical raw material for the production of spices,cosmetics,pharmaceuticals,pesticides,and fungicides.The direct derivation oflevulinic acid from cellulose markedly mitigates dependence on fossil fuels,consequently driving down expenses and fostering sustainable development.This review focuses on the catalytic conversion of cellulose to levulinic acid,covering aspects including reaction pathways,process methods,catalytic systems,and factors influencing catalytic performance.The current status of multi-step and one-step processes for producing levulinic acid from cellulose is briefly described.Furthermore,we discuss how process conditions such as temperature and solvent affect the product yield.Additionally,this review analyzes catalysts used in the production of levulinic acid from cellulose,especially focusing on solid acid catalysts.The influences on activity are summarized,considering factors such as active site regulation and pore structure design.Based on these findings,we propose future prospects for catalyst design and preparation,process advancement,and the utilization of cellulosic raw materials in the conversion of cellulose to levulinic acid.

关 键 词：纤维素 乙酰丙酸 固体酸催化剂 活性位 孔结构 

分 类 号：TK6[动力工程及工程热物理—生物能] O622.3[理学—有机化学]