溶解-沉淀-GC/MS法快速评估Tritan塑料中2,2,4,4-四甲基-1,3-环丁二醇的迁移量水平  

Dissipation-Precipitation-GC/MS Method for Rapid Assessment of 2,2,4,4-Tetramethyl-1,3-Cyclobutanediol Migration Level in Tritan Plastics

作　　者：阿文伟 曾铭 梁霞 韦昱 吴泽春 范颖莹 陈湘颖 曾莹 李丹 A Wenwei;ZENG Ming;LIANG Xia;WEI Yu;WU Zechun;FAN Yingying;CHEN Xiangying;ZENG Ying;LI Dan(Guangzhou Customs Technical Center,Guangzhou 510275,China;China National Center for Food Safety Risk Assessment,Beijing 100022,China)

机构地区：[1]广州海关技术中心,广州510275 [2]国家食品安全风险评估中心,北京100022

出　　处：《包装工程》2025年第3期136-142,共7页Packaging Engineering

基　　金：国家重点研发项目(2022YFF0607202)。

摘　　要：目的建立溶解-沉淀-GC/MS法测定萃特(Tritan)塑料中2,2,4,4-四甲基-1,3-环丁二醇残留量的分析方法,通过残留量100%迁移的假设,快速评估目标物的最大迁移量。方法样品经六氟异丙醇溶解后,用乙醇做沉淀剂将高聚物充分沉淀,上清液浓缩过滤后供气相色谱-质谱联用仪测定,外标法定量。结果2,2,4,4-四甲基-1,3-环丁二醇在0.080~40 mg/kg范围内线性关系良好,相关系数均>0.995。该方法的检出限为0.04 mg/kg,定量限为0.080 mg/kg,加标回收率为92.5%~105%,相对标准偏差(n=6)为3.0%~5.0%。通过对实际样品进行测试和评估,表明残留量检测方法具有较高的准确度和较好的重现性。结论建立的残留量筛查法可在实际工作中用于快速评估Tritan塑料制品中2,2,4,4-四甲基-1,3-环丁二醇的迁移量水平。The work aims to develop an analytical method for determining the residual amount of 2,2,4,4-tetramethyl-1,3-cyclobutanediol Tritan plastic based on the assumption of 100%migration of the residue using a dissolution-precipitation-GC/MS method,so as to rapidly assess the maximum migration amount of the target substance.After dissolving the sample in hexafluoroisopropanol,ethanol was used as a precipitant to fully precipitate the polymer.The supernatant,after concentration and filtration,was analyzed by gas chromatography-mass spectrometry with external standard quantification.2,2,4,4-tetramethyl-1,3-cyclobutanediol exhibited good linearity within the range of 0.080 to 40 mg/kg,with correlation coefficients all greater than 0.995.The limits of detection and limits of quantification of the method were 0.04 mg/kg and 0.080 mg/kg.The recoveries ranged from 92.5% to 105%,with the relative standard deviation(n=6)of 3.0%~5.0%.Testing and evaluation of actual samples demonstrated that the residue detection method had high accuracy and good reproducibility.In conclusion,this residue screening method can be used for rapid assessment of the migration level of 2,2,4,4-tetramethyl-1,3-cyclobutanediol in Tritan plastic products.

关 键 词：Tritan塑料 2 2 4 4-四甲基-1 3-环丁二醇 溶解-沉淀 气相色谱-质谱法 残留量 

分 类 号：TG142.1-5[一般工业技术—材料科学与工程]