布鲁氏菌病隐性感染者流行病学特征分析  

Epidemiological characteristics of asymptomatic Brucellosis

作　　者：韩丽红[1] 张峰 马淑一[1] 闫佳敏 沈琦宇 HAN Lihong;ZHANG Feng;MA Shuyi;YAN Jiamin;SHEN Qiyu(Baotou Medical College,Baotou 014040,China;Baotou Mongolian Traditional Chinese Medicine Hospital)

机构地区：[1]包头医学院,内蒙古包头014040 [2]包头市蒙医中医医院

出　　处：《包头医学院学报》2025年第1期78-80,共3页Journal of Baotou Medical College

基　　金：内蒙古自治区自然科学基金项目(2018LH08080);内蒙古自治区卫生健康委医疗卫生科技计划项目(202201374,202201390);包头医学院布鲁氏菌病研究(培育)团队(bycxtd-14)。

摘　　要：目的:通过对比布鲁氏菌病(又称布病)隐性感染者和急性布病患者职业、年龄、性别和试管凝集试验(SAT)抗体滴度的差异,了解布病隐性感染者基本情况,为预防和治疗布病提供基础信息。方法:采取完全随机抽样的方法选取锡盟地区2019年1月~12月依据《布鲁氏菌病诊断标准》确诊的急性布病患者164例和隐性布病感染者160例。患者年龄和经对数转换后的SAT滴度用两独立样本t检验比较;职业和性别用χ^(2)检验比较。结果:两组职业进行比较(χ^(2)=15.837,P<0.05),差异有统计学意义;两组年龄和SAT滴度比较均具有统计学意义(P<0.05),隐性感染者年龄低于急性布病组,抗体滴度高于急性布病患者;两组性别比较(χ^(2)=0.018,P>0.05),差异无统计学意义。结论:布病感染状况可能与职业、年龄、SAT抗体滴度有关。Objective:To investigate the differences in the occupation,age,gender and serum agglutination test(SAT)antibody titers between asymptomatic Brucellosis cases and acute Brucellosis cases,with the purpose of providing basic information to the prevention and treatment of Brucellosis.Methods:Using a completely random sampling method,164 acute brucellosis patients and 160 latent brucellosis infections diagnosed according to the"Diagnostic Criteria for Brucellosis"in the Ximeng region from January to December 2019 were selected as the research subjects.Compare the patient's age and SAT titers after logarithmic transformation using two independent sample t-tests;Compare occupation and gender usingχ^(2) test.Results:Comparison of occupation between the two groups of patients,the differences were statistically significant(χ^(2)=15.837,P<0.05).Comparison of age and SAT titer in the two groups,the differences were statistically significant(P<0.05).Patients with asymptomatic Brucellosis were younger than acute Brucellosis cases,and the SAT titer of symptomatic Brucellosis cases was higher than acute Brucellosis cases.There was no significant difference in gender between the two groups of patients(χ^(2)=0.018,P>0.05).Conclusion:The infection status of brucellosis may be related to occupation,age,and SAT antibody titers.

关 键 词：布鲁氏菌病 隐性感染 流行病学特征分析 

分 类 号：R181.3[医药卫生—流行病学] R516.7[医药卫生—公共卫生与预防医学]