美托洛尔治疗老年高血压性心脏病室性心律失常的有效性分析  

Effectiveness analysis of metoprolol in the treatment of ventricular arrhythmia in elderly patients with hypertensive heart disease

作　　者：齐丽梅 QI Li-mei(Chifeng Hospital,Inner Mongolia,Chifeng 024000,China)

机构地区：[1]内蒙古赤峰市医院,024000

出　　处：《中国实用医药》2025年第2期95-98,共4页China Practical Medicine

摘　　要：目的分析将美托洛尔应用在老年高血压性心脏病室性心律失常患者中的治疗效果。方法将177例老年高血压性心脏病室性心律失常患者经随机数字法分为观察组(89例)和对照组(88例)。对照组予以常规治疗方案,观察组在对照组的基础上联合美托洛尔治疗。对比两组的临床疗效及临床相关指标。结果观察组治疗显效39例、有效31例、好转16例、无效3例,对照组治疗显效22例、有效28例、好转28例、无效10例。观察组的临床疗效高于对照组,差异有统计学意义(P<0.05)。治疗前,两组的舒张压、收缩压、左室射血分数、QT离散度(QTd)对比,差异无统计学意义(P>0.05);治疗后,观察组的舒张压(80.79±9.41)mm Hg(1 mm Hg=0.133 kPa)、收缩压(121.61±14.16)mm Hg、左室射血分数(55.52±6.47)%、QTd(50.69±5.90)ms相较于对照组的(93.47±10.85)mm Hg、(129.44±15.03)mm Hg、(46.88±5.44)%、(56.61±6.57)ms更优,差异有统计学意义(P<0.05)。结论将美托洛尔应用在老年高血压性心脏病室性心律失常患者的治疗之中能有效提升患者的疗效,改善患者的症状,值得推荐。Objective To analyze the effect of metoprolol in the treatment of ventricular arrhythmia in elderly patients with hypertensive heart disease.Methods A total of 177 elderly patients with hypertensive heart disease and ventricular arrhythmia were randomly divided into an observation group(89 cases)and a control group(88 cases).The control group was given conventional treatment,and the observation group was combined with metoprolol on the basis of the control group.The clinical efficacy and relevant clinical indexes of the two groups were compared.Results In the observation group,the treatment was significantly effective in 39 cases,effective in 31 cases,improved in 16 cases and ineffective in 3 cases;in the control group,the treatment was significantly effective in 22 cases,effective in 28 cases,improved in 28 cases,and ineffective in 10 cases.The clinical efficacy of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in diastolic blood pressure,systolic blood pressure,left ventricular ejection fraction and QT dispersion(QTd)between the two groups(P>0.05).After treatment,the diastolic blood pressure,systolic blood pressure,left ventricular ejection fraction and QTd were(80.79±9.41)mm Hg(1 mm Hg=0.133 kPa),(121.61±14.16)mm Hg,(55.52±6.47)%and(50.69±5.90)ms in the observation group,which were better than(93.47±10.85)mm Hg,(129.44±15.03)mm Hg,(46.88±5.44)%and(56.61±6.57)ms in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of metoprolol in the treatment of ventricular arrhythmia in elderly patients with hypertensive heart disease can effectively improve the curative effect of patients and improve the symptoms of patients,and it is worth recommending.

关 键 词：美托洛尔 老年 高血压 心脏病 室性心律失常 疗效 

分 类 号：R541.7[医药卫生—心血管疾病] R541.3[医药卫生—内科学]