富血小板血浆联合运动疗法治疗青年半月板损伤短期疗效观察  

Observation the Short-Term Efficacy of Platelet-Rich Plasma Therapy Combined with Exercise Therapy Meniscus Injury in Young People

作　　者：凌泽莎 白新刚 阙方绪 唐召兵 董超 周婷婷 庞日朝 Ling Zesha;Bai Xingang;Que Fangxu(Department of Rehabilitation,General Hospital of Western Theater of Chinese PLA,Chengdu,Sichuan 610083,China)

机构地区：[1]中国人民解放军西部战区总医院康复医学科,四川成都610083

出　　处：《四川医学》2025年第1期78-83,共6页Sichuan Medical Journal

摘　　要：目的分析富血小板血浆联合运动疗法对青年半月板损伤的短期疗效。方法选取2022年11月至2023年4月于我院门诊就诊的青年半月板损伤患者(年龄≤44岁)60例为研究对象,病程>3个月,MRI检查半月板损伤Ⅰ~Ⅱ级,按随机数字表法分为A、B、C组(每组20例),A组接受富血小板血浆治疗,B组接受运动疗法治疗,C组接受富血小板血浆联合运动疗法治疗。血小板血浆每周注射1次,每次注射5 ml,连续5周;运动训练30 min/次,5次/周,连续5周。治疗前后进行VAS评分、JOA半月板损伤治疗后效果评分、改良Lysholm膝关节运动水平评分、膝关节MRI检查。结果研究期间,A组脱落1例,C组脱落2例,最终共纳入57例患者。3组患者治疗前VAS评分、JOA半月板损伤治疗后效果评分、改良Lysholm膝关节运动水平评分比较,差异无统计学意义(P>0.05)。经过1个疗程治疗(5周)后,各组疼痛较治疗前均有减轻,运动能力均有明显改善,差异有统计学意义(P<0.01);其中A组疼痛较B组疼痛改善明显,差异有统计学意义(P<0.05),B组膝关节功能改善优于A组,差异有统计学意义(P<0.05),C组疼痛改善、膝关节运动功能提升均明显优于A、B组,差异有统计学意义(P<0.01);疗程结束1月后随访,膝关节MRI检查Stoller分类未见半月板形态上有明显改善。结论富血小板血浆联合运动疗法可在短期内缓解青年半月板损伤所致膝关节疼痛及提升膝关节运动功能,疗效显著,值得临床推广。Objective To observe short-term clinical efficacy of platelet rich plasma combined with exercise therapy to treat meniscus injury in young people.Methods From November 2022 to April 2023,60 young patients with meniscus injury treated in the outpatient department were selected as research subjects.The course of disease was more than 3 months.According to the date of treatment,they were randomly divided into three groups.Group A received platelet-rich plasma treatment,group B received exercise therapy,and group C received platelet-rich plasma combined with exercise therapy.The platelet-rich plasma was injected once a week with 5 ml each time for 5 weeks,exercise training for 30 minutes every time,once a day for 5 weeks,Lysholm score,JOA meniscus injury score,visual analogue pain score(VAS)were performed before and after treatment in three groups and between groups.Results During study period,1 cases were lost in A group and 2 cases were lost in C group.Total 57 patients were finally included.Before treatment,there was no significant difference in general data between groups(P>0.05).After a course of treatment,the pain of each group after treatment was reduced compared with that before treatment,and exercise ability was significantly improved with statistically significant difference(P<0.01).The improvement of pain in group A was significantly better than that in group B with statistically significant difference(P<0.05).The improvement of knee joint function in group B was better than that in group A with statistically significant difference(P<0.05).The improvement of pain and knee joint function in group C were significantly better than those in group A and group B with statistically significant difference(P<0.01).There was no change in meniscus morphology in Stoller classification of knee joint MRI at 1 month follow-up.Conclusion Platelet-rich plasma combined with exercise therapy in the treatment of young meniscus injury could relieve pain,improve motor function in short term.The curative effect is worthy of clin

关 键 词：富血小板血浆 运动疗法 半月板损伤 

分 类 号：R49[医药卫生—康复医学]