当归川芎汤联合缩宫素治疗产后子宫复旧不良血瘀证临床研究  

Clinical Study on Danggui Chuanxiong Decoction Combined with Oxytocin for Postpartum Subinvolution of Uterus with Blood Stasis Syndrome

作　　者：梅燕 袁慧慧 MEI Yan;YUAN Huihui(Department of Perinatal Health Care,Tianshui and Wulin Street Community Health Service Center of Gongshu District of Hangzhou,Hangzhou Zhejiang 310003,China;Department of Chinese Medicine,Tianshui and Wulin Street Community Health Service Center of)

机构地区：[1]杭州市拱墅区天水武林街道社区卫生服务中心围产保健科,浙江杭州310003 [2]杭州市拱墅区天水武林街道社区卫生服务中心中医科,浙江杭州310003

出　　处：《新中医》2025年第3期44-47,共4页New Chinese Medicine

摘　　要：目的:观察当归川芎汤联合缩宫素治疗产后子宫复旧不良血瘀证的临床疗效。方法:选择2021年3月—2023年3月杭州市拱墅区天水武林街道社区卫生服务中心就诊的剖宫产后子宫复旧不良血瘀证患者76例,按照随机数字表法分为对照组、观察组各38例。对照组给予缩宫素治疗,观察组在对照组基础上加用当归川芎汤治疗。比较2组治疗前后子宫三径线之和、血瘀证症状评分、凝血功能相关指标、恶露量,比较2组临床疗效、恶露持续时间及不良反应发生情况。结果:治疗后,观察组总有效率94.74%(36/38),高于对照组73.68%(28/38)(P<0.05)。治疗后,2组子宫三径线之和、血瘀证症状评分及血清纤维蛋白原(FIB)水平均较治疗前降低(P<0.05),恶露量减少(P<0.05),凝血酶时间(TT)延长(P<0.05),且观察组子宫三径线之和、血瘀证症状评分及血清FIB水平低于对照组(P<0.05),恶露量少于对照组(P<0.05),TT长于对照组(P<0.05)。2组治疗前后凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)比较,差异无统计学意义(P>0.05)。观察组恶露持续时间短于对照组(P<0.05)。2组均无不良反应发生。结论:当归川芎汤联合缩宫素治疗产后子宫复旧不良血瘀证临床疗效显著,能够缩短患者恶露持续时间,改善凝血功能,安全性较高。Objective:To observe the clinical effect of the combination use of Danggui Chuanxiong Decoction and oxytocin on postpartum subinvolution of uterus with blood stasis syndrome.Methods:A total of 76 patients with postpartum subinvolution of uterus with blood stasis syndrome after cesarean section treated at Tianshui and Wulin Street Community Health Service Center of Gongshu District of Hangzhou from March 2021 to March 2023 were selected and divided into the control group and the observation group according to the random number table method,with 38 cases in each group.The control group was treated with oxytocin,and the observation group was additionally treated with Danggui Chuanxiong Decoction based on the treatment of the control group.The sum of three diameters of the uterus,the scores of symptom of blood stasis syndrome,the related indexes of coagulation function and the amount of lochia were compared before and after treatment,and the clinical effects,duration of lochia and incidence of adverse reactions were compared between the two groups.Results:After treatment,the total effective rate was 94.74%(36/38)in the observation group,higher than that of 73.68%(28/38)in the control group(P<0.05).After treatment,the sum of of three diameters of the uterus,scores of symptom of blood stasis syndrome and levels of serum fibrinogen(FIB)in the two groups were reduced when compared with those before treatment(P<0.05),the amount of lochia was dwindled(P<0.05),and thrombin time(TT)was prolonged(P<0.05);the sum of three diameters of the uterus,score of symptom of blood stasis syndrome and serum FIB level in the observation group were lower than those in the control group(P<0.05),the amount of lochia was less than that in the control group(P<0.05),and the TT was longer than that in the control group(P<0.05).There was no significant difference being found in the comparisons of prothrombin time(PT)and activated partial thromboplastin time(APTT)between the two groups before and after treatment(P>0.05).The duration of lochia in t

关 键 词：产后子宫复旧不良 血瘀证 当归川芎汤 凝血功能 

分 类 号：R714.69[医药卫生—妇产科学]