基于罗丹明衍生物的次氯酸响应型荧光探针的构建及其性能研究  

Construction and Performance Study of Hypochlorous Acid-Responsive Fluorescent Probes Based on Rhodamine Derivatives

作　　者：满若琳 张君美 成奋民[1] 郝远强 陈述[1] 曾荣今[1] 张培盛[1] MAN Ruo-lin;ZHANG Jun-mei;CHENG Fen-min;HAO Yuan-qiang;CHEN Shu;ZENG Rong-jin;ZHANG Pei-sheng(College of Chemistry and Chemical Engineering,Hunan University of Science and Technology,Hunan xiangtan 411201)

机构地区：[1]湖南科技大学化学化工学院,湖南湘潭411201

出　　处：《胶体与聚合物》2024年第4期155-158,共4页Chinese Journal of Colloid & Polymer

基　　金：国家自然科学基金项目(52173278,52273290);湖南省自然科学基金项目(2020JJ3021,2021JJ10029);湖南省科技创新计划项目(2022RC1075)。

摘　　要：以罗丹明B酰肼为基本骨架,设计合成了一种能够对次氯酸(HClO)进行特异性检测的小分子荧光探针(RBHD)。该探针本身呈现出丹磺酰胺的蓝绿色荧光,当HClO存在时,探针分子中的亚氨基被氧化,进一步水解释放出罗丹明B基团,体系荧光由蓝绿色变为橙红色,实现了对HClO的特异性检测。此外,该探针能够对HClO实现快速响应(响应时间10 s),表现出高灵敏度和优良的选择性,并且成功应用于环境水中HClO的检测。A small molecule fluorescent probe(RBHD)was designed and synthesized using rhodamine B hydrazide as the basic skeleton,which can specifically detect hypochlorous acid(HClO).The probe itself shows the blue-green fluorescence of dansulfonamide.The imine in the probe molecule is oxidized in the presence of HClO,and further hydrolysis releases the rhodamine B group.The fluorescence of the system is changed from blue-green to orange-red,which realizes the specific detection of HClO.In addition,the probe was able to achieve a rapid response to HClO(response time 10 s),showing high sensitivity and excellent selectivity,and was successfully applied to the detection of HClO in environmental water.

关 键 词：荧光探针 罗丹明B 丹磺酰胺 次氯酸 

分 类 号：TQ31[化学工程—高聚物工业] O63[理学—高分子化学]