限食疗法对食欲调节激素的影响  

Effects of calorie restriction therapy on appetite-regulating hormone

作　　者：李元媛 何志伟 韦晓[2] 陈国芳[1] 刘超[1] Li Yuanyuan;He Zhiwei;Wei Xiao;Chen Guofang;Liu Chao(Department of Endocrinology,Nanjing Integrated Traditional Chinese and Western Medicine Hospital,Nanjing University of Chinese Medicine,Jiangsu Provincial Academy of Traditional Chinese Medicine,Nanjing210028,China;Key Laboratory for Research on Thyroid Disease Diagnosis and Treatment,Nanjing Integrated Traditional Chinese and Western Medicine Hospital,Nanjing University of Chinese Medicine,Jiangsu Provincial Academy of Traditional Chinese Medicine,Nanjing210028,China)

机构地区：[1]南京中医药大学附属中西医结合医院、江苏省中医药研究院内分泌科,南京210028 [2]南京中医药大学附属中西医结合医院、江苏省中医药研究院瘿病诊治重点研究室,南京210028

出　　处：《中国基层医药》2025年第1期156-160,共5页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：限食疗法在防治代谢性疾病领域受到广泛重视,限食后,多种食欲调节激素发生变化,如瘦素、胰岛素、胰淀素的降低,肽YY、胰高血糖素样肽1、胰多肽的升高,这些变化在调节人体摄食过程、改善糖脂代谢、维持能量平衡等方面具有重要作用。笔者就限食疗法对食欲调节激素的相关影响,深入探讨限食疗法治疗代谢性疾病的作用机制,为肥胖、2型糖尿病等代谢性疾病的长期缓解提供防治思路。Calorie restriction has garnered significant attention in the prevention and treatment of metabolic diseases.During calorie restriction,various appetite-regulating hormones undergo changes,including a decrease in leptin,insulin,and amylin,along with an increase in peptide YY,glucagon-like peptide 1,and pancreatic polypeptide.These hormonal changes play a crucial role in regulating the body's feeding processes,improving glucose and lipid metabolism,and maintaining energy balance.In this paper,we discuss the effects of dietary restriction therapy on appetite-regulating hormones and the mechanisms by which this therapy aids in the treatment of metabolic diseases.Our goal is to provide insights for the prevention and long-term management of metabolic disorders such as obesity and type 2 diabetes.

关 键 词：限食 食欲调节 糖尿病 2型 肥胖症 营养和代谢性疾病 瘦素 胰岛素 胰多肽 能量代谢 综述 

分 类 号：R58[医药卫生—内分泌]