Research Progress on the Process Optimization and Stability Improvement of Third-generation Cephalosporins  

作　　者：Hao LIU Yanxi LAI Shengjiu GU Kaimei ZHU 

机构地区：[1]College of Pharmacy,Guilin Medical University,Guilin 541199,China

出　　处：《Medicinal Plant》2025年第1期23-26,共4页药用植物(英文)

基　　金：Supported by the Funds from Central Government for Guiding Local Science and Technology Development(ZY20230102);Planning Project of Scientific Research and Technology Development in Guilin(20220104-4,20210202-1);Science and Technology Planing Project of Guangxi(Guike AB24010263).

摘　　要：The latest progress in the process optimization and stability improvement of third-generation cephalosporins in recent years was reviewed.The introduction of green chemistry,enzyme catalysis,nanotechnology,lyophilization,and nitrogen-filled packaging technologies can only improve production efficiency and reduce the generation of by-products,but also significantly extend the shelf life of drugs.In the future,process automation and intelligent technology will further optimize the large-scale production process,and the combination of nanotechnology and precision drug delivery will promote the improvement of effect in clinical applications.

关 键 词：Third-generation cephalosporins Process optimization NANOTECHNOLOGY Green chemistry Drug stability 

分 类 号：R978.1[医药卫生—药品]