DKI结合DCE-MRI对腮腺肿瘤的鉴别诊断价值及与病理诊断的一致性  

The Differential Diagnostic Value of DKI Combined with DCE-MRI for Parotid Gland Tumors and Its Consistency with Pathological Diagnosis

作　　者：王梦莹 王嘉麟 卫孟佳 张博文 吉小曦 WANG Meng-ying;WANG Jia-lin;WEI Meng-jia;ZHANG Bo-wen;Ji Xiao-xi(Department of Radiology,Qinhuangdao Seaport Hospital,Qinhuangdao 066000,Hebei Province,China)

机构地区：[1]秦皇岛市海港医院放射科,河北秦皇岛066000

出　　处：《中国CT和MRI杂志》2025年第2期67-70,共4页Chinese Journal of CT and MRI

摘　　要：目的探讨扩散峰度成像(DKI)结合动态对比增强磁共振成像(DCE-MRI)鉴别诊断腮腺肿瘤的价值及与病理诊断的一致性。方法选取2021年6月至2024年7月在我院治疗的腮腺肿瘤患者70例,给予DKI、DCE-MRI检查,分析DKI、DCE-MRI及结合诊断腮腺肿瘤良恶性病变与病理诊断的一致性,探讨其临床应用价值。结果70例患者,病理结果确诊恶性病变20例,良性病变50例。DKI、DCE-MRI及两者结合诊断腮腺肿瘤与病理诊断一致性Kappa值分别为0.621、0.690和0.722,P<0.05。DKI结合DCE-MRI诊断腮腺肿瘤恶性病变的灵敏性、阴性预测值分别为100.00%和100.00%,高于DKI、DCE-MRI单独检查,但差异比较无统计学意义(P>0.05)。腮腺肿瘤恶性病变平均扩散系数(MD)为(1.02±0.30)×10^(-3)mm^(2)/s,明显低于良性病变(P<0.05),而平均峰度系数(MK)为(1.18±0.34),明显高于良性病变(P<0.05)。腮腺肿瘤良恶性病变时间信号强度(TIC)曲线类型比较差异有统计学意义(P<0.05),恶性病变TIC曲线C型比例较高,达到70.00%;腮腺肿瘤恶性病变血管外细胞外间隙容积比(Ve)为(0.20±0.08),低于腮腺肿瘤良性病变(P<0.05)。结论DKI结合DCE-MRI鉴别诊断腮腺肿瘤有一定价值,与病理诊断一致性较好;DKI、DCE-MRI可为鉴别诊断腮腺肿瘤提供客观参数。Objective To explore the value of diffusion-kurtosis imaging(DKI)combined with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in the differential diagnosis of parotid gland tumors and its consistency with pathological diagnosis.Methods 70 patients with parotid gland tumors treated in our hospital from June 2021 to July 2024 were selected,DKI and DCE-MRI examinations were performed to analyze the value of DKI,DCE-MRI,and their combined diagnosis of benign and malignant lesions in parotid gland tumors.Results In 70 patients,pathological results confirmed 20 cases of malignant lesions and 50 cases of benign lesions.The Kappa values for the consistency between DK,DCE-MRI,and their combined diagnosis of parotid gland tumors and pathological diagnosis were 0.621,0.690,and 0.722,respectively,with P<0.05.The sensitivity and negative predictive value of DK combined with DCE-MRI in diagnosing malignant lesions of parotid gland tumors were 100.00%and 100.00%,respectively,which were higher than DK and DCE-MRI examinations,but the difference was not statistically significant(P>0.05).The mean diffusion coefficient(MD)of malignant lesions in parotid gland tumors is(1.02±0.30)×10^(-3)mm^(2)/s,which was significantly lower than that of benign lesions(P<0.05),while the mean kurtosis coefficient(MK)was(1.18±0.34),which was significantly higher than that of benign lesions(P<0.05).There was a statistically significant difference in the type of time signal intensity(TIC)curve between benign and malignant lesions of parotid gland tumors(P<0.05),and the proportion of TIC curve type C in malignant lesions was higher,reaching 70.00%.The extracellular space volume ratio(V_e)of malignant lesions of parotid gland tumors was(0.20±0.08),which was lower than that of benign lesions of parotid gland tumors(P<0.05).Conclusion DKI combined with DCE-MRI has certain value in the differential diagnosis of parotid gland tumors and is consistent with pathological diagnosis.DKI and DCE-MRI can provide objective parameters for differenti

关 键 词：扩散峰度成像 动态对比增强磁共振成像 腮腺肿瘤 鉴别诊断 

分 类 号：R445.2[医药卫生—影像医学与核医学]