原发性肾上腺淋巴瘤的影像学表现及免疫组化特点分析  

Imaging Manifestations and Immunohisto chemistry of Primary Adrenal Lymphoma

作　　者：孙志磊 周丹枫 SUN Zhi-lei;ZHOU Dan-feng(Department of radiology,the First Affiliated Hospital of Soochow University,Suzhou 215006,Jiangsu Province,China)

机构地区：[1]苏州大学附属第一医院放射科,江苏苏州215006

出　　处：《中国CT和MRI杂志》2025年第2期134-136,共3页Chinese Journal of CT and MRI

摘　　要：目的 探讨原发性肾上腺淋巴瘤(PAL)的影像学表现特点,以提高诊断的准确性。方法 回顾性分析2012年5月至2021年12月经手术或穿刺病理证实的12例PAL患者的CT和MRI影像资料,包括病灶部位、大小、形态、密度、强化方式及病灶周围情况等,并复习相关文献。结果 12例患者中,8例单侧发生,4例双侧发生,共计16个病灶。病灶长径范围为2.4-10.2cm。CT平扫11例CT扫描中9例密度均匀,3例不均匀。2例MRI病例中T1WI呈低信号,T2WI呈高信号,其中1例T2WI不均匀(病灶内坏死),所有病灶边界均清晰。增强扫描表现:9例患者CT增强后7例动脉期及静脉期见轻度均匀强化,未见实性成分强化者2例;2例患者MRI增强后呈轻-中度强化,其内见血管穿行,不均质强化1例。免疫组织化学Ki-67阳性表达率100%,CD79、CD20、Bcl-6、MUM1、Bcl-2大部分表达阳性。结论 PAL的影像学表现及免疫组化表达具有一定特点,在该病诊断中具有价值。Objective To investigate the imaging features of primary adrenal lymphoma(PAL) in order to improve the accuracy of diagnosis. Methods Retrospective analysis was done on CT and MRI imaging data of 12 PAL patients from May 2012 to December 2021, which were verified by surgery or puncture pathology.The analysis included a review of pertinent literature and an analysis of lesion location, size, shape, density, enhancement mode, and surrounding circumstances. Results Of the 12 patients, 8 were unilateral and 4 were bilateral, with a total of 16 lesions. The length and diameter of the lesions ranged from 2.4-10.2cm. Among the 11 CT scan cases, 9 cases had uniform density and 3 cases had uneven density. In 2 MRI cases,T1WI showed low signal and T2WI showed high signal. In 1 case, T2WI was uneven(intrafocal necrosis), and the boundaries of all lesions were clear. Enhancement scanning findings: After CT enhancement, 7 of 9 patients saw mild uniform enhancement in arterial and venous phases, and 2 patients did not see solid component enhancement. After MRI enhancement, 2 patients showed mild to moderate enhancement, vascular passage was found in them, and uneven enhancement was found in 1 patient. Immunohistochemical Ki-67 positive expression rate was 100%, CD79, CD20, Bcl-6, MUM1, Bcl-2 were mostly positive. Conclusion The imaging findings and immunohistochemical expression of PAL have certain characteristics, which is valuable in the diagnosis of PAL.

关 键 词：肾上腺 淋巴瘤 影像学 免疫组化 

分 类 号：R445.2[医药卫生—影像医学与核医学]