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作 者:周景华 李炜[1] 吴梦云 李奎 谭秀洪[1] 孙军[1] Zhou Jinghua;Li Wei;Wu Mengyun;Li Kui;Tan Xiuhong;Sun Jun(Chongqing Municipal Center for Disease Control and Prevention,Institute of Occupational and Radiological Health,Chongqing 400707,China)
机构地区:[1]重庆市疾病预防控制中心职业卫生与放射卫生所,重庆400707
出 处:《中华放射医学与防护杂志》2025年第1期43-48,共6页Chinese Journal of Radiological Medicine and Protection
基 金:重庆市科卫联合医学科研项目(2022ZDXM034,2023QNXM034)。
摘 要:目的了解重庆市非铀矿工氡暴露剂量水平和健康状况。方法2022年6月至2023年12月,对重庆市6座正常生产的非铀金属矿山110名配合度较好的男性矿工开展基本情况、氡暴露情况和职业健康状况调查。采用logistic回归模型统计分析矿工氡个人剂量对矿工染色体畸变分析、微核检查、肿瘤标志物和肺部CT影像学检查异常的影响。结果氡个人剂量计监测结果显示,3名矿工年剂量>2 mSv。logistic回归分析显示,肺部CT影像学检查异常与矿工年龄、工龄、饮酒有关(χ^(2)=12.18、9.63、4.87,P<0.05),与吸烟和氡个人剂量无显著相关。氡个人剂量与肿瘤标志物异常有关,每增加1 mSv氡及其子体产生的有效剂量,异常风险增加2.25倍(χ^(2)=4.57,P<0.05)。结论重庆部分矿工个人年剂量>2 mSv,氡个人剂量与肺癌血清肿瘤标志物异常相关,需关注矿工氡暴露风险监测,定期开展健康检查,完善矿工群体的健康监护。Objective To investigate the radon exposure levels and health effects among non⁃uranium miners in Chongqing.Methods From June 2022 to December 2023,a survey was carried out on basic information,radon exposure and occupational health status of 110 male miners with good cooperation attitudes in 6 non⁃uranium metal mines in normal operation in Chongqing.The logistic regression model was utilized to statistically analyze the impact of miners′individual radon doses on abnormalities in chromosomal aberration analysis,micronucleus examination,tumor marker tests,and pulmonary CT imaging.Results Monitoring results from passive integrated radon personal dosimeters indicated that three miners had an annual dose exceeding 2 mSv.Logistic regression analysis revealed that abnormalities in pulmonary CT imaging were associated with miners′age,tenure,and alcohol consumption(χ^(2)=12.18,9.63,4.87,P<0.05),with no significant correlation with smoking or individual radon dose.There was a significant correlation between individual radon dose and abnormalities in tumor markers;for every additional 1 mSv of effective dose from radon and its progeny,the risk of abnormality increased by 2.25 times(χ^(2)=4.57,P<0.05).Conclusions Some miners in Chongqing are exposed to an annual dose exceeding 2 mSv,and there is a correlation between individual radon doses and abnormalities in lung cancer serum tumor markers.It is necessary to focus on monitoring the radon exposure risks for miners,carry out regular health checks,and enhance the health protection for the miner population.
分 类 号:R144.1[医药卫生—公共卫生与预防医学]
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