Catalytic detoxification of mitoxantrone by graphitic carbon nitride(g-C_(3)N_(4))supported Fe/Pd bimetallic nanoparticles  

作　　者：Qianyu Xu Haoyang Fu Jiyuan Gu Liyu Lei Lan Ling 

机构地区：[1]State Key Laboratory for Pollution Control and Resource Reuse,College of Environmental Science and Engineering,Tongji University,Shanghai 200092,China

出　　处：《Journal of Environmental Sciences》2025年第2期614-624,共11页环境科学学报(英文版)

基　　金：Financial support from the National Natural Science Foundation of China (No.22176147);the National Science Fund for Excellent Young Scholars of China (No.21822607);the Fundamental Research Funds for Central Universities (No.22120230295);the State Key Laboratory for Pollution Control is acknowledged.

摘　　要：The overuse of antibiotics and antitumor drugs has resulted in more and more extensive pollution of water bodies with organic drugs,causing detrimental ecological effects,which have attracted attention towards effective and sustainable methods for antibiotics and antitumor drug degradation.Here,the hybrid nanomaterial(g-C_(3)N_(4)@Fe/Pd)was synthesized and used to remove a kind of both an antibiotic and antitumor drug named mitoxantrone(MTX)with 92.0%removal efficiency,and the MTX removal capacity is 450 mg/g.After exposing to the hybrid material the MTX aqueous solution changed color from dark blue to lighter progressively,and LC-UV results of residual solutions showthat a newpeak at 3.0min(MTX:13.2min)after removal by g-C_(3)N_(4)@Fe/Pd appears,with the simultaneous detection of intermediate products indicating that g-C_(3)N_(4)@Fe/Pd indeed degrades MTX.Detailed mass spectrometric analysis suggests that the nuclear mass ratio decreased from 445.2(M+1H)to 126.0(M+1H),169.1(M+1H),239.2(M+1H),267.3(M+1H),285.2(M+1H),371.4(M+1H)and 415.2(M+1H),and the maximum proportion(5.63%)substance of all degradation products(126.0(M+1H))is 40-100 times less toxic than MTX.A mechanism for the removal and degradation of mitoxantrone was proposed.Besides,actual water experiments confirmed that the maximum removal capacity of MTX by g-C_(3)N_(4)@Fe/Pd is up to 492.4 mg/g(0.02 g/L,10 ppm).

关 键 词：DEGRADATION LC-QTOF-MS Nanoparticles MITOXANTRONE Aqueous solution 

分 类 号：R71[医药卫生—妇产科学]