PKEP治疗大体积前列腺增生患者的疗效和安全性观察  

Efficacy and Safety of PKEP in the Treatment of Massive Benign Prostatic Hyperplasia

作　　者：李军昭[1] 李健[2] 戚超群 LI Junzhao;LI Jian;QI Chaoqun(Shangshui People's Hospital,Zhoukou Henan 466100)

机构地区：[1]河南省商水县人民医院泌尿外科,河南周口466100 [2]河南省周口市中心医院泌尿外科,河南周口466000

出　　处：《医学临床研究》2025年第1期95-98,共4页Journal of Clinical Research

摘　　要：【目的】探讨经尿道前列腺等离子剜除术(PKEP)治疗大体积前列腺增生患者的疗效和安全性。【方法】选取2020年1月至2021年1月本院收治的112例大体积前列腺增生患者,按随机数字表法将其分为观察组与对照组,每组56例。观察组患者行PKEP,对照组患者行经尿道前列腺电切术(TUPKP)。比较两组患者的围术期指标及术后并发症发生情况,在术后对患者随访3个月,比较两组患者手术前后的随访指标、肾功能、性功能。【结果】观察组手术时间、术中出血量、留置导管时间、住院时间少于对照组,腺体切除重量高于对照组(P<0.05)。术后,两组前列腺症状评分(IPSS)、生活质量评分(QOL)、残余尿量显著低于术前,最大尿流率显著高于术前(P<0.05),但两组比较,差异无统计学意义(P>0.05);术后,两组尿素氮(BUN)、肌酐(Scr)显著低于术前(P<0.05),但两组比较,差异无统计学意义(P>0.05);观察组术后6个月、术后12个月国际勃起功能指数评分简表(IIEF-5)评分均显著低于术前,高于对照组(P<0.05);观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。【结论】PKEP治疗大体积前列腺增生患者的疗效和安全性较好。【Objective】To investigate the efficacy and safety of plasmakinetic enucleation of prostate(PKEP)in the treatment of massive benign prostatic hyperplasia.【Methods】A total of 112 patients with massive prostatic hyperplasia who were treated in our hospital from January 2020 to January 2021 were selected and divided into the observation group(n=56)and the control group(n=56).The patients in the observation group underwent PKEP,while the patients in the control group underwent transurethral plasma kinetic resection of prostate(TUPKP).The perioperative indexes and postoperative complications of the two groups of patients were compared.The patients were followed up for 3 months after the operation,then the follow-up related indexes,renal function,and sexual function of the two groups of patients before and after the operation were compared.【Results】The operation time,intraoperative blood loss,indwelling catheter time and hospital stay in the observation group were significantly shorter than those in the control group,and the weight of gland removal was significantly higher than that in the control group(P<0.05).The postoperative prostate symptom score(IPSS),quality of life score(QOL)and residual urine volume of the two groups were significantly lower than those before operation,and the maximum urinary flow rate was significantly higher than that before operation(P<0.05),but there were no significant differences of those parameters between the two groups(P>0.05).The postoperative blood urea nitrogen(BUN)and creatinine(Scr)of the two groups were significantly lower than those before the operation(P<0.05),however,there were no significantly different levels of BUN and Scr between the two groups(P>0.05).The scores of the International Index of Erectile Function(IIEF-5)at 6 months and 12 months after operation in the observation group were significantly lower than those before operation of the observation and those in the control group(P<0.05).The total incidence of complications in the observation group signific

关 键 词：前列腺增生 经尿道前列腺切除术 治疗结果 

分 类 号：R697.32[医药卫生—泌尿科学]