温针灸联合医用几丁糖治疗老年膝骨关节炎患者的临床疗效  

Clinical Efficacy of Warm Acupuncture Combined with Medical Chitosan in the Treatment of Elderly Knee Osteoarthritis

作　　者：苏伟 柯蔚 刘建 彭圣洁 SU Wei;KE Wei;LIU Jian(Department of Orthopaedics,Putuo District Hospital of Traditional Chinese Medicine,Shanghai 200062)

机构地区：[1]上海市普陀区中医医院骨伤科,上海200062

出　　处：《医学临床研究》2025年第1期105-108,共4页Journal of Clinical Research

摘　　要：【目的】探讨温针灸联合医用几丁糖治疗老年膝骨关节炎患者的临床疗效。【方法】选取2020年1月至2024年6月在本院接受治疗的300例老年膝骨关节炎患者,按随机数字表法分为观察组和对照组,每组150例。对照组接受常规治疗(关节腔内注射医用几丁糖治疗),观察组在常规治疗的基础上接受温针灸治疗。比较两组临床疗效、膝关节活动度(ROM)、疼痛程度[视觉模拟评分法(VAS)]、炎症因子[白介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)、基质金属蛋白酶-9(MMP-9)、透明质酸(HA)、类风湿因子(RF)]水平以及不良反应发生率。【结果】治疗后,观察组临床疗效和ROM优于对照组(P<0.05),VAS评分、不良反应发生率及IL-1β、TNF-α、MMP-9、HA、RF水平低于对照组(P<0.05)。【结论】温针灸联合医用几丁糖治疗老年膝骨关节炎患者,可显著提高ROM,减轻疼痛程度,降低炎症因子水平和不良反应发生率,具有较高的临床应用价值。【Objective】To explore the clinical efficacy of warm acupuncture combined with medical chitosan in the treatment of elderly patients with knee osteoarthritis.【Methods】From January 2020 to June 2024,a total of 300 elderly patients with knee osteoarthritis were selected for treatment.They were randomly divided into the observation group and the control group,with 150 patients in each group.Patients in the control group received conventional treatment,namely intra-articular injection of medical chitosan,while those in the observation group received warm acupuncture in addition to conventional treatment.Clinical efficacy,knee joint range of motion(ROM),pain level[Visual Analogue Scale(VAS)],inflammatory factors[Interleukin-1β(IL-1β),Tumor Necrosis Factor-α(TNF-α),Matrix Metalloproteinase-9(MMP-9),Hyaluronic Acid(HA),Rheumatoid Factor(RF)],and incidence of adverse reactions were compared between the two groups.【Results】After treatment,the clinical efficacy and ROM in the observation group were higher than those in the control group(P<0.05),while VAS scores,IL-1β,TNF-α,MMP-9,HA,RF levels and the incidence of adverse reactions were lower than those in the control group(P<0.05).【Conclusion】Warm acupuncture combined with medical chitosan can significantly improve knee joint mobility,relieve pain,reduce inflammatory factor levels,and has fewer adverse reactions.It showes high clinical value.

关 键 词：骨关节炎 膝 针灸疗法 壳多糖 老年人 治疗结果 

分 类 号：R684.3[医药卫生—骨科学]