某精神病专科医院2021—2023年多重耐药菌感染流行病学分布  

Epidemiological distribution of multidrug-resistant bacterial infections in a psychiatric specialty hospital from 2021 to 2023

作　　者：陈运迷 邓少玲 胡丽婵[1] 劳永志 郑兴[1] 岳磊[2] 施海姗[1] 黄兴兵[3] 缪天养 CHEN Yun-mi;DENG Shao-ling;HU Li-can;LAO Yong-zhi;ZHENG Xing;YUE Lei;SHI Hai-shan;HUANG Xing-bing;MIAO Tian-yang(Department of Hospital Infection Control,the Affiliated Brain Hospital,Guangzhou Medical University,Guangzhou Medical University,Guangzhou 510370,Guangdong,China;不详)

机构地区：[1]广州医科大学附属脑科医院医院感染管理科,广东广州510370 [2]广州医科大学附属脑科医院检验科,广东广州510370 [3]广州医科大学附属脑科医院精神科、广东省神经科学疾病研究重点实验室、神经致病基因与离子通道病省部共建重点实验室,广东广州510370

出　　处：《广东医学》2025年第1期102-106,共5页Guangdong Medical Journal

基　　金：广州市科技计划项目(2023A03J0831);广州市研究型医院项目。

摘　　要：目的分析精神病专科医院多重耐药菌感染的流行病学特征,为做好多重耐药菌医院感染防控提供依据,降低住院患者感染多重耐药菌的概率。方法通过医院感染管理信息监测系统收集细菌室检出的2021年1月至2023年12月住院患者临床常见的多重耐药菌的资料,分析多重耐药菌的三间分布等流行病学特征,使用SPSS 25.0数据分析软件对数据进行统计分析。结果细菌室检出多重耐药菌感染病例共917例次,男性患者576例,女性患者341例,检验男女性别分布差异有统计学意义(χ^(2)=60.2,P<0.01),男性患者多重耐药菌感染率为2.56%,高于女性患者多重耐药菌感染率1.62%(χ^(2)=46.3,P<0.01);男性患者平均年龄(68.5±14.8)岁,女性患者平均年龄(71.6±15.7)岁,差异有统计学意义(P<0.01),多重耐药菌感染患者在人群中的性别分布和年龄分布差异有统计学意义(P<0.05)。多重耐药菌检出强度最高的科室由高至低依次为ICU、精神科综合病区、老年精神科、神经科、精神科慢性病区、普通精神科。检出多重耐药菌类型与季度的分布差异有统计学意义(χ^(2)=1923,P<0.01)。结论多重耐药菌在男性患者中高发于女性患者,且男性患者的发生年龄小于女性患者,多重耐药菌在不同的季节分布不一致,且在第一季度高发,具有季节性的特征。Objective To analyze the epidemiological characteristics of multidrug-resistant(MDR)bacterial infections in a psychiatric specialty hospital,providing evidence for effective infection control and prevention measures to reduce the likelihood of patients acquiring such infections during hospitalization.Methods Data on common clinical MDR bacterial infections in hospitalized patients from January 2021 to December 2023 were collected through the hospital infection management information monitoring system.The three-way distribution of MDR bacteria was analyzed,and statistical analysis was performed using SPSS 25.0 software.Results A total of 917 cases of MDR bacterial infections were identified in the hospital′s microbiology department.Of these,576 were male patients and 341 were female patients,with significant differences in gender distribution(χ^(2)=60.2,P<0.01).The infection rate in male patients(2.56%)was significantly higher than that in female patients(1.62%)(χ^(2)=46.3,P<0.01).The average age of male patients was(68.5±14.8)years,while the average age of female patients was(71.6±15.7)years,showing a statistically significant difference(P<0.01).The distribution of MDR bacterial infections varied significantly across different hospital departments,with the highest detection rates observed in the ICU,general psychiatric wards,geriatric psychiatry,neurology,chronic psychiatric wards,and general psychiatric wards in decreasing order.There was also a statistically significant seasonal variation in the detection of MDR bacteria,with the first quarter showing the highest infection rates(χ^(2)=1923,P<0.01).Conclusion MDR bacterial infections are more prevalent in male patients compared to females,with male patients being younger on average.The distribution of these infections varies across different seasons,with a significant peak in the first quarter,indicating a seasonal pattern of occurrence.

关 键 词：疾病预防与控制 多重耐药菌 精神病专科医院 流行病学 

分 类 号：R181.2[医药卫生—流行病学] R372[医药卫生—公共卫生与预防医学]