11%精甲·咯·嘧菌种子处理悬浮剂中2,6-二甲基苯胺高效液相色谱分析  

Determination of 2,6-dimethylaniline in metalaxyl-M·fludioxonil·azoxystrobin 11% FS by HPLC

作　　者：高杰 段丽芳 刘莹 陈银银 石凯威 GAO Jie;DUAN Lifang;LIU Ying;CHEN Yinyin;SHI Kaiwei(Institute for the Control of Agrochemicals,Ministry of Agriculture and Rural Affairs,Beijing100125,China;Shandong Academy of Pesticide Sciences,Jinan250000,China;Guizhou Jiandee Technology Co.,Ltd.,Guiyang550014,China)

机构地区：[1]农业农村部农药检定所,北京100125 [2]山东省农药科学研究院,济南250000 [3]贵州健安德科技有限公司,贵阳550014

出　　处：《现代农药》2025年第1期54-56,76,共4页MODERN AGROCHEMICALS

摘　　要：为准确测定甲霜灵和精甲霜灵产品中相关杂质2,6-二甲基苯胺,建立了高效液相色谱分析方法。该方法以乙腈和磷酸缓冲溶液为流动相,使用C18柱分离,二极管阵列检测器(232 nm)检测,对11%精甲·咯·嘧菌种子处理悬浮剂中2,6-二甲基苯胺进行定量分析。结果表明,在质量浓度50.90~407.17 mg/L,方法的线性相关系数为0.99958,相对标准偏差为3.7%,定量限为2.08 mg/kg,平均添加回收率为104%。该方法分离效果好,具有较好的精密度和准确度。A method for determination of related impurity 2,6-dimethylaniline in metalaxyl and metalaxyl-M was developed by HPLC.Using acetonitrile and phosphate buffer solution as mobile phase,2,6-dimethylaniline in metalaxyl-M·fludioxonil·azoxystrobin 11%FS was separated by a column packed with C18 and determined by DAD at 232 nm wavelength.The analytical method showed good linear relationship between 50.90 to 407.17 mg/L,with the linear correlation coefficient of 0.99958.The relative standard deviation was 3.7%,the limit of quantificationtion(LOQ)was 2.08 mg/kg and the mean recovery was 104%.The developed method showed good separation,precision and accuracy.

关 键 词：精甲霜灵 2 6-二甲基苯胺 杂质 高效液相色谱 分析 

分 类 号：TQ450.7[化学工程—农药化工]