慢性鼻窦炎患者鼻窦分泌物的需氧菌检验分析  

Analysis of aerobic bacteria in nasal discharge of patients with chronic sinusitis

作　　者：程凤菊 Cheng Fengju(Department of Laboratory,Dongping County People's Hospital,Tai'an,Shandong 271500,China)

机构地区：[1]东平县人民医院,山东泰安271500

出　　处：《中国医学文摘(耳鼻咽喉科学)》2025年第1期120-123,共4页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：目的探讨慢性鼻窦炎鼻窦分泌物需氧菌检验结果与疾病发生的相关性,分析鼻窦分泌物对鼻窦炎的诊断价值。方法:对于我院收治的慢性鼻窦炎患者,共搜集50名,时间分布在2021年1月到2022年12月期间,作为疾病组;同期入院检查的健康者,共搜集50名,作为健康组;采集鼻窦内分泌物检测两组需氧菌分布特征,多元线性回归分析需氧菌与慢性鼻窦炎发病的相关性。结果:疾病组需氧菌阳性率及表皮葡萄球菌、金黄葡萄球菌、草色链球菌阳性率更高,对比健康组,P值均<0.05(差异有统计学意义)。根据标准化回归系数的绝对值大小,表皮葡萄球菌、金黄葡萄球菌、草色链球菌阳性率与慢性鼻窦炎患病相关(P值<0.05)。根据药敏试验结果,对患者抗菌活性较好的抗生素包括环丙沙星、万古霉素、庆大霉素、复方新诺明,抗菌活性较低的抗生素为青霉素、苯唑西林、红霉素;将活性较好的抗生素用于治疗中,治疗后临床总有效率88.00%(44/50)。结论:慢性鼻窦炎患者鼻窦分泌物内有较高的需氧菌检出率,需氧菌阳性率与慢性鼻窦炎病情之间的关系密切,根据菌落的药敏试验结果来制定治疗方案可以提高疗效。l Objective To investigate the correlation between the results of aerobic examination of sinus secretions and the occurrence of chronic sinusitis,and to analyze the diagnostic value of sinus secretions for sinusitis.Methods A total of 50 patients with chronic sinusitis admitted to our hospital from January 2021 to December 2022 were collected as disease group.A total of 50 healthy patients admitted to hospital for examination during the same period were collected as the health group;The distribution characteristics of aerobic bacteria in the two groups were detected by collecting nasal secretions,and the correlation between aerobic bacteria and chronic sinusitis was analyzed by multiple linear regression.Results The positive rates of aerobic bacteria and Staphylococcus epidermidis,Staphylococcus aureus and streptococcus aureus in the disease group were higher than those in the healthy group,and the P values were all<0.05(the difference was statistically significant).According to the absolute value of standardized regression coefficient,the positive rates of Staphylococcus epidermidis,Staphylococcus aureus and streptococcus aureus were associated with chronic sinusitis(P<0.05).According to the results of drug sensitivity test,the antibiotics with good antibacterial activity for patients included ciprofloxacin,vancomycin,gentamicin and cotrimoxazole,while the antibiotics with low antibacterial activity were penicillin,oxacillin and erythromycin.The total clinical effective rate after treatment was 88.00%(44/50).Conclusion There is a high detection rate of aerobic bacteria in the nasal secretions of patients with chronic sinusitis,and there is a close relationship between the positive rate of aerobic bacteria and chronic sinusitis.The therapeutic plan can be improved according to the results of drug sensitivity test.

关 键 词：慢性鼻窦炎 鼻窦分泌物 需氧菌检验 药敏试验 治疗方案 

分 类 号：R76[医药卫生—耳鼻咽喉科]