普米克令舒雾化吸入治疗危重新生儿因气管插管导致的喉头水肿的效果研究  

Effect of Pulmicort Respules Aerosol Inhalation on Laryngeal Edema Caused by Tracheal Intubation in Critical Neonates

作　　者：吕璐璐 Lv Lulu(Department of Neonatology and Pediatrics,Huantai County Maternal and Child Health Hospital,Zibo City,Shandong Province,256400,China)

机构地区：[1]桓台县妇幼保健院,山东淄博256400

出　　处：《中国医学文摘(耳鼻咽喉科学)》2025年第1期124-126,共3页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：目的分析雾化吸入普米克令舒对危重新生儿因气管插管导致的喉头水肿的治疗效果。方法选择2020年7月~2023年7月期间在本院行气管插管操作并因此导致喉头水肿的70例危重新生儿作为研究对象,以电脑随机进行分组,对照组35例,研究组35例。对照组在拔管前静脉注射地塞米松,研究组在拔管后雾化吸入普米克令舒。对比两组的临床疗效以及治疗前后的二氧化碳分压、氧分压、心率、呼吸频率。结果研究组总有效率(97.14%)高于对照组(77.14%),差异有统计学意义(P<0.05)。治疗前,两组的二氧化碳分压、氧分压、心率、呼吸频率无明显不同,差异无统计学意义(P>0.05);治疗后,研究组的二氧化碳分压、心率、呼吸频率较治疗前及对照组同期检测结果相对更低,氧分压较治疗前及对照组同期检测结果相对更高,差异有统计学意义(P<0.05)。结论雾化吸入普米克令舒对危重新生儿因气管插管导致的喉头水肿有显著治疗效果,避免患儿动脉血气和生命体征出现较大波动。Objective To analyze the therapeutic effect of aerosol inhalation of Pulmicort Respules on laryngeal edema caused by tracheal intubation in critically ill neonates.Methods From July 2020 to July 2023,70 critically ill newborns with laryngeal edema caused by tracheal intubation in our hospital were randomly divided into control group(50 cases)and study group(50 cases)by computer.The control group was injected dexamethasone intravenously before extubation,while the study group inhaled plmicort after extubation.The clinical efficacy,partial pressure of carbon dioxide,partial pressure of oxygen,heart rate and respiratory rate before and after treatment were compared between two groups.Results The total effective rate of the study group(97.14%)was significantly higher than that of the control group(77.14%),withstatistical significance(P<0.05).There was no statistical difference between the two groups in the values of PaCO_(2),PaO_(2),heart rate and respiratory rate before treatment(P>0.05).After treatment,the partial pressure of carbon dioxide,heart rate and respiratory rate in the study group were lower than those before treatment and those in the control group at the same time,and the partial pressure of oxygen was higher than those before treatment and those in the control group at the same time,with statistical significance(P<0.05).Conclusion Pulmicort Respules inhalation has significant therapeutic effect on laryngeal edema caused by tracheal intubation in critically ill neonates,and avoids the fluctuation of arterial blood gas and vital signs.

关 键 词：普米克令舒:雾化吸入治疗 危重新生儿 气管插管 喉头水肿 治疗效果 

分 类 号：R47[医药卫生—护理学]