肺康复训练联合布地奈德福莫特罗对重度慢性阻塞性肺疾病患者肺功能及日常生活能力的影响  

Effects of pulmonary rehabilitation training combined with budesonide and formoterol on pulmonary function and activity of daily living in patients with severe chronic obstructive pulmonary disease

作　　者：陈翀 黄明华 CHEN Chong;HUANG Minghua(Rehabilitation Department,Nanxiang Town Community Health Service Center,Jiading District,Shanghai 201800;Rehabilitation Department,Traditional Chinese Medicine Hospital of Putuo District,Shanghai 200333,China)

机构地区：[1]上海市嘉定区南翔镇社区卫生服务中心康复科,上海201800 [2]上海市普陀区中医医院康复科,上海200333

出　　处：《临床医学研究与实践》2025年第5期57-60,共4页Clinical Research and Practice

摘　　要：目的探究肺康复训练联合布地奈德福莫特罗对重度慢性阻塞性肺疾病(COPD)患者肺功能及日常生活能力的影响。方法选取2018年2月至2021年6月收治的87例重度COPD患者为研究对象,采用随机数字表法将其分为对照组(43例)和观察组(44例)。对照组给予布地奈德福莫特罗吸入粉雾剂治疗,观察组在对照组基础上进行肺康复训练。比较两组的肺功能、血气分析指标、6 min步行试验(6MWT)及日常生活能力。结果治疗后,两组的呼气峰值流速(PEF)、第1秒用力呼气容积(FEV1)、用力肺活量(FVC)均高于治疗前,且观察组高于对照组(P<0.05)。治疗后,两组的二氧化碳分压(PCO_(2))低于治疗前,氧分压(PO_(2))、血氧饱和度(SO_(2))均高于治疗前,且观察组优于对照组(P<0.05)。治疗后,两组的6MWT长于治疗前,圣乔治呼吸问卷(SGRQ)评分低于治疗前,且观察组优于对照组(P<0.05)。结论肺康复训练联合布地奈德福莫特罗可改善重度COPD患者的肺功能,提高日常生活能力,值得临床推广。Objective To explore the effects of pulmonary rehabilitation training combined with budesonide and formoterol on pulmonary function and activity of daily living in patients with severe chronic obstructive pulmonary disease(COPD).Methods A total of 87 patients with severe COPD admitted from February 2018 to June 2021 were selected as the research objects and divided into control group(43 cases)and observation group(44 cases)by random number table method.The control group was treated with budesonide and formoterol fumarate powder for inhalation,and the observation group was treated with pulmonary rehabilitation training on the basis of the control group.The pulmonary function,blood gas analysis indexes,6 minute walk test(6MWT)and activity of daily living were compared between the two groups.Results After treatment,peak expiratory flow(PEF),forced expiratory volume in one second(FEV1)and forced vital capacity(FVC)in the two groups were higher than those before treatment,and those in the observation group were higher than the control group(P<0.05).After treatment,partial pressure of carbon dioxide(PCO_(2))in the two groups was lower than that before treatment,partial pressure of oxygen(PO_(2))and oxygen saturation(SO_(2))were higher than those before treatment,and those in the observation group were better than the control group(P<0.05).After treatment,the 6MWT of the two groups was longer than that before treatment,the St.George's Respiratory Questionnaire(SGRQ)score was lower than that before treatment,and those in the observation group were better than the control group(P<0.05).Conclusion Pulmonary rehabilitation training combined with budesonide and formoterol can improve the pulmonary function and activity of daily living of patients with severe COPD,which is worthy of clinical promotion.

关 键 词：肺康复训练 布地奈德福莫特罗吸入粉雾剂 慢性阻塞性肺疾病 肺功能 日常生活能力 

分 类 号：R563[医药卫生—呼吸系统]