强力定眩片联合氟桂利嗪治疗脑动脉硬化性眩晕症的有效性与安全性  

Efficacy and safety of Qiangli Dingxuan tablets combined with flunarizine in treatment of cerebral arteriosclerotic vertigo

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作  者:胡蓉蓉 王培 姜盼盼 HU Rongrong;WANG Pei;JIANG Panpan(Neurology Department,the Second Hospital of Weinan,Weinan 714000;Neurology Department,Baishui County Hospital,Weinan 715600,China)

机构地区:[1]渭南市第二医院神经内科,陕西渭南714000 [2]白水县医院神经内科,陕西渭南715600

出  处:《临床医学研究与实践》2025年第5期109-112,共4页Clinical Research and Practice

摘  要:目的分析强力定眩片联合氟桂利嗪治疗脑动脉硬化性眩晕症的有效性与安全性。方法选取2020年1月至2022年12月收治的80例脑动脉硬化性眩晕症患者为研究对象,以随机数字表法将患者分为单药组(40例,氟桂利嗪治疗)和联合组(40例,强力定眩片联合氟桂利嗪治疗)。比较两组的治疗效果。结果联合组的治疗总有效率高于单药组(P<0.05)。治疗后,联合组的症状评分低于单药组(P<0.05)。治疗后,联合组的总胆固醇(TC)、甘油三酯(TG)及低密度脂蛋白(LDL)水平低于单药组,高密度脂蛋白(HDL)水平高于单药组(P<0.05)。治疗后,联合组大脑前动脉(ACA)、大脑中动脉(MCA)、大脑后动脉(PCA)的平均血流速度(Vm)大于单药组,阻力指数(RI)小于单药组(P<0.05)。两组的不良反应总发生率无明显差异(P>0.05)。结论强力定眩片联合氟桂利嗪治疗脑动脉硬化性眩晕症患者可取得理想的效果。Objective To analyze the efficacy and safety of Qiangli Dingxuan tablets combined with flunarizine in treatment of cerebral arteriosclerotic vertigo.Methods A total of 80 patients with cerebral arteriosclerotic vertigo admitted from January 2020 to December 2022 were selected as the research objects.The patients were divided into single drug group(40 cases,flunarizine treatment)and combined group(40 cases,Qiangli Dingxuan tablets combined with flunarizine treatment)by random number table method.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the combined group was higher than that in the single drug group(P<0.05).After treatment,the symptom score of the combined group was lower than that of the single drug group(P<0.05).After treatment,the levels of total cholesterol(TC),triglyceride(TG)and low density lipoprotein(LDL)in the combined group were lower than those in the single drug group,and the level of high density lipoprotein(HDL)was higher than that in the single drug group(P<0.05).After treatment,the mean blood flow velocity(Vm)of anterior cerebral artery(ACA),middle cerebral artery(MCA)and posterior cerebral artery(PCA)in the combined group were larger than those in the single drug group,and resistance index(RI)was smaller than that in the single drug group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Qiangli Dingxuan tablets combined with flunarizine in the treatment of patients with cerebral arteriosclerotic vertigo can achieve ideal effect.

关 键 词:脑动脉硬化性眩晕症 强力定眩片 氟桂利嗪 

分 类 号:R255.3[医药卫生—中医内科学]

 

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