甲状旁腺全切联合前臂自体移植术在三发性甲状旁腺功能亢进症中的应用价值分析  

Analysis of the Application Value of Total Parathyroidectomy Combined with Forearm Autotransplantation in Triple Essential Hyperparathyroidism

作　　者：罗晓敏 史红霞 郭芳[1] 宋银平 张俊杰[1] Luo Xiaomin;Shi Hongxia;Guo Fang;Song Yinping;Zhang Junjie(The Fifth Clinacal Medical College of Henan University of Chinese Medicine(Zhengzhou People's Hospital),Zhengzhou Henan 450000,China)

机构地区：[1]河南中医药大学第五临床医学院(郑州人民医院),河南郑州450000

出　　处：《哈尔滨医药》2024年第4期12-15,共4页Harbin Medical Journal

基　　金：河南省医学科技攻关计划联合共建项目(2018020827)。

摘　　要：目的探究甲状旁腺全切联合前臂自体移植术治疗三发性甲状旁腺功能亢进症的价值。方法选取收治三发性甲状旁腺功能亢进症患者144例,随机分为对照组与研究组各72例。对比两组患者生化指标、生活质量、HGB、ALB水平、症状评分及临床疗效。结果治疗后,研究组患者iPTH、Ca、P、Mg指标、骨痛VAS、瘙痒VAS及睡眠SRSS低于对照组(P<0.05);治疗后,研究组患者ALP指标、生活质量、治疗有效率高于对照组(P<0.05);治疗前与治疗后,两组患者HGB、ALB水平差异无统计学意义(P>0.05)。结论对于患有三发性甲状旁腺功能亢进症患者,采用甲状旁腺全切与前臂自体移植手段治疗三发性甲状旁腺功能亢进症患者在临床上表现出良好的疗效,这不仅能显著改善患者的生化指标,还能提升其生活质量。Objective Exploring the value of total parathyroidectomy combined with forearm autotransplantation in the treatment of triple hyperparathyroidism.Method 144 patients with triple essential hyperparathyroidism were randomLy divided into a control group and a study group,with 72 cases in each group.The control group underwent total parathyroidectomy for treatment,while the study group underwent forearm autologous transplantation on the basis of the control group.The biochemical indicators,quality of life,HGB,ALB levels,symptom scores,and clinical efficacy of the two groups of patients were compared.Result After treatment,the patients in the study had lower levels of iPTH,Ca,P,Mg,bone pain VAS,pruritus VAS and sleep SRSS than the control group(P<0.05).After treatment,the patients in the study had higher levels of ALP,quality of life and treatment efficacy than the control group(P<0.05).Conclusion In patients with triple hyperparathyroidism,the combination of total parathyroidectomy and forearm autograft showed good clinical efficacy,which not only significantly improved the patients'biochemical indicators,but also their quality of life.

关 键 词：三发性甲状旁腺功能亢进症 甲状旁腺全切 前臂自体移植术 生化指标 

分 类 号：R581[医药卫生—内分泌]