LncRNAs:expanding horizons in drug development and disease treatment Author links open overlay panel  

长链非编码RNA:药物研发与临床诊疗的新方向

作　　者：Zhizhuo Wang Junfeng Wang Wenfei Wu Chengyu Shi Ying Wang Yu Chen Fangzhou Liu Shanshan Xie Aifu Lin 王治卓;王峻峰;吴文菲;石成瑜;王颖;陈妤;刘方舟;谢珊珊;林爱福

机构地区：[1]International School of Medicine,International Institutes of Medicine,The 4th Affiliated Hospital of Zhejiang University School of Medicine,Yiwu 322000,China [2]MOE Laboratory of Biosystem Homeostasis and Protection,College of Life Sciences,Zhejiang University,Hangzhou 310058,China [3]Children’s Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,Hangzhou 310052,China [4]Department of Cell Biology,Zhejiang University School of Medicine,Hangzhou 310058,China [5]Cancer Center,Zhejiang University,Hangzhou 310058,China [6]Key Laboratory for Cell and Gene Engineering of Zhejiang Province,Hangzhou 310058,China [7]Future Health Laboratory,Innovation Center of Yangtze River Delta,Zhejiang University,Jiaxing 314100,China [8]Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Hangzhou 310009,China [9]Faculty of Health Sciences,University of Macao,Macao 999078,China

出　　处：《Science Bulletin》2025年第3期287-289,共3页科学通报(英文版)

基　　金：supported by the National Natural Science Fund for Distinguished Young Scholars(32225014);the Noncommunicable Chronic Diseases-National Science and Technology Major Project(2023ZD0507500);the National Natural Science Foundation of China(81672791,81872300,and 82172899);the National Key R&D Program of China(2021YFC2700903);the“Lingyan”R&D Research and Development Project(2023C03023);the Zhejiang Provincial Natural Science Fund for Distinguished Young Scholars of China(LR18C060002 and LR22H160002);the Fundamental Research Funds for the Central Universities(K20220228).

摘　　要：Extensive genome profiling studies have identified thousands of long non-coding RNAs(lncRNAs)associated with human cancer.LncRNAs are emerging elements through which the complex process of cancer development and progression can be understood.Thus,it is crucial to include an examination of lncRNAs when studying human cancer,especially when researching the clinical challenges of relapse and recurrence following targeted therapy[1].

关 键 词：HORIZON EXPANDING treatment 

分 类 号：R73[医药卫生—肿瘤]