甘油三酯-葡萄糖指数在2型糖尿病及其微血管并发症中的研究进展  

Research progress of triglyceride-glucose index in type 2 diabetes mellitus and its microvascular complications

作　　者：徐帆 陈小春 官诗芬 黄宏毅 晏赛亚 许荣 XU Fan;CHEN Xiao-chun;GUAN Shi-fen;HUANG Hong-yi;YAN Sai-ya;XU Rong(The First Clinical Medical School of Gannan Medical University;Endocrine Department,The First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi 341000)

机构地区：[1]赣南医科大学第一临床医学院 [2]赣南医科大学第一附属医院内分泌科,江西赣州341000

出　　处：《赣南医科大学学报》2025年第1期58-62,73,共6页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：江西省教育厅科学技术研究项目(GJJ2201434);江西省卫生健康委员会科技计划项目(202210870);赣南医学院第一附属医院博士启动基金项目(QD082)。

摘　　要：2型糖尿病(Type 2 diabetes mellitus,T2DM)是全球最常见的慢性病之一,其发病机制主要是胰岛素抵抗(Insulin resistance,IR)和(或)胰岛素分泌不足。目前T2DM及其微血管并发症的患病率持续增加,治疗效果差。为了早期防治T2DM及其微血管并发症,研究人员提出甘油三酯-葡萄糖(Triglyceride-glucose,TyG)指数作为预测糖尿病及其微血管并发症的有效指标,TyG指数简单可靠,具有较高的临床价值。本文结合近年相关文献对TyG指数与T2DM及其微血管并发症的相关性进行综述。文献复习结果表明,TyG指数与T2DM及其微血管并发症相关,因此认为TyG指数可以作为T2DM及其微血管并发症的有效预测指标。Type 2 diabetes mellitus(T2DM)is one of the most common chronic diseases in the worldwide.Its pathogenesis is mainly insulin resistance(IR)and/or insufficient insulin secretion.At present,the prevalence of T2DM and its microvascular complications continues to increase,and the treatment effect is still poor.In order to early prevent and treat T2DM and its microvascular complications,researchers proposed triglyceride-glucose(TyG)index as an effective index to predict diabetes and its microvascular complications.TyG index is simple and reliable,and has high clinical value.This review combined with the relevant literature in recent years to elaborate the correlation between TyG index and T2DM and its microvascular complications.The results of literature review showed that TyG index was correlated with T2DM and its microvascular complications,and TyG index could be used as an effective predictor of T2DM and its microvascular complications.

关 键 词：甘油三酯-葡萄糖指数 2型糖尿病 2型糖尿病微血管并发症 

分 类 号：R587.2[医药卫生—内分泌]