老年2型糖尿病患者骨骼肌质量与内脏脂肪面积比值和心血管疾病风险的相关性分析  

Relationship between skeletal muscle mass to visceral fat area ratio and cardiovascular disease risk in elderly patients with type 2 diabetes mellitus

作　　者：王婧欣 王月菊[1] 唐海英[1] WANG Jingxin;WANG Yueju;TANG Haiying(Department of Geriatrics,the First Affiliated Hospital of Soochow University,Suzhou 215006,Jiangsu,China)

机构地区：[1]苏州大学附属第一医院老年医学科,江苏苏州215006

出　　处：《中国现代医生》2025年第3期45-48,60,共5页China Modern Doctor

摘　　要：目的探讨老年2型糖尿病(type 2 diabetes mellitus,T2DM)患者骨骼肌质量与内脏脂肪面积比值(skeletal muscle mass to visceral fat area ratio,SVR)和心血管疾病(cardiovascular disease,CVD)风险之间的关系。方法选取2022年10月至2023年12月于苏州大学附属第一医院老年医学科就诊的144例T2DM患者,根据生物电阻抗测量对SVR进行评估。应用中国动脉粥样硬化性心血管疾病风险预测研究(prediction for ASCVD risk in China,China-PAR)风险模型对T2DM患者的心血管病风险进行评估。统计分析SVR与China-PAR风险评分之间的相关性。结果T2DM患者CVD风险评分随SVR的降低而升高(P<0.001)。高危组患者的SVR低于低危组,腰围高于低危组,差异有统计学意义(P<0.05)。两组患者的BMI比较差异无统计学意义(P=0.1229)。在校正混杂因素后,SVR与China-PAR风险评分之间存在独立相关性(β=-2.744,P=0.007)。结论SVR较低的T2DM患者患CVD的风险更高,SVR水平与老年T2DM患者CVD风险呈显著负相关,SVR可能是评估老年CVD风险的有价值的参数。Objective To explore the relationship between skeletal muscle mass to visceral fat area ratio(SVR)and cardiovascular disease(CVD)risk in elderly patients with type 2 diabetes mellitus(T2DM).Methods 144 T2DM patients who visited the Department of Geriatrics,the First Affiliated Hospital of Soochow University from October 2022 to December 2023 were selected to evaluate SVR based on bioelectrical impedance measurements.The risk model of prediction for ASCVD risk in China(China-PAR)was used to assess the risk of cardiovascular disease in T2DM patients.Statistical analysis of the correlation between SVR and China-PAR risk scores.Results The CVD risk score of T2DM patients increased with the decrease of SVR(P<0.001).The SVR of high-risk group patients was lower than that of low-risk group patients,and their waist circumference was higher than that of low-risk group patients,with statistical significance(P<0.05).There was no statistically significant difference in BMI between two groups of patients(P=0.1229).After adjusting for confounding factors,there was an independent correlation between SVR and China PAR risk scores(β=-2.744,P=0.007).Conclusion T2DM patients with lower SVR have a higher risk of developing CVD,and SVR levels are significantly negatively correlated with CVD risk in elderly T2DM patients.SVR may be a valuable parameter for assessing CVD risk in the elderly.

关 键 词：2型糖尿病 骨骼肌质量与内脏脂肪面积比值 心血管疾病 风险评估 中国动脉粥样硬化性心血管疾病风险预测研究 

分 类 号：R587.2[医药卫生—内分泌]